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Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
Stöppler D, Macpherson A, Smith-Penzel S, Basse N, Lecomte F, Deboves H, Taylor RD, Norman T, Porter J, Waters LC, Westwood M, Cossins B, Cain K, White J, Griffin R, Prosser C, Kelm S, Sullivan AH, Fox D 3rd, Carr MD, Henry A, Taylor R, Meier BH, Oschkinat H, Lawson AD. Stöppler D, et al. Among authors: prosser c. PLoS Biol. 2018 May 21;16(5):e2006192. doi: 10.1371/journal.pbio.2006192. eCollection 2018 May. PLoS Biol. 2018. PMID: 29782488 Free PMC article.
Automated protein-ligand interaction screening by mass spectrometry.
Maple HJ, Garlish RA, Rigau-Roca L, Porter J, Whitcombe I, Prosser CE, Kennedy J, Henry AJ, Taylor RJ, Crump MP, Crosby J. Maple HJ, et al. J Med Chem. 2012 Jan 26;55(2):837-51. doi: 10.1021/jm201347k. Epub 2012 Jan 12. J Med Chem. 2012. PMID: 22148839
Conformational heterogeneity in antibody-protein antigen recognition: implications for high affinity protein complex formation.
Addis PW, Hall CJ, Bruton S, Veverka V, Wilkinson IC, Muskett FW, Renshaw PS, Prosser CE, Carrington B, Lawson ADG, Griffin R, Taylor RJ, Waters LC, Henry AJ, Carr MD. Addis PW, et al. Among authors: prosser ce. J Biol Chem. 2014 Mar 7;289(10):7200-7210. doi: 10.1074/jbc.M113.492215. Epub 2014 Jan 16. J Biol Chem. 2014. PMID: 24436329 Free PMC article.
Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.
Patel S, Barkell AM, Gupta D, Strong SL, Bruton S, Muskett FW, Addis PW, Renshaw PS, Slocombe PM, Doyle C, Clargo A, Taylor RJ, Prosser CE, Henry AJ, Robinson MK, Waters LC, Holdsworth G, Carr MD. Patel S, et al. Among authors: prosser ce. J Biol Chem. 2018 Aug 3;293(31):12149-12166. doi: 10.1074/jbc.RA118.002918. Epub 2018 Jun 20. J Biol Chem. 2018. PMID: 29925589 Free PMC article.
Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery.
Walker K, Baravalle R, Holyfield R, Kalms J, Wright H, Seewooruthun C, Muskett FW, Scott-Tucker A, Merritt A, Henry A, Lawson ADG, Hall G, Prosser C, Carr MD. Walker K, et al. Among authors: prosser c. Front Immunol. 2023 Jul 6;14:1216967. doi: 10.3389/fimmu.2023.1216967. eCollection 2023. Front Immunol. 2023. PMID: 37483614 Free PMC article.
276 results