Carr MD - Search Results

1

Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.

Stöppler D, Macpherson A, Smith-Penzel S, Basse N, Lecomte F, Deboves H, Taylor RD, Norman T, Porter J, Waters LC, Westwood M, Cossins B, Cain K, White J, Griffin R, Prosser C, Kelm S, Sullivan AH, Fox D 3rd, Carr MD, Henry A, Taylor R, Meier BH, Oschkinat H, Lawson AD. Stöppler D, et al. Among authors: carr md. PLoS Biol. 2018 May 21;16(5):e2006192. doi: 10.1371/journal.pbio.2006192. eCollection 2018 May. PLoS Biol. 2018. PMID: 29782488 Free PMC article.

2

NMR studies of multiple conformations in complexes of Lactobacillus casei dihydrofolate reductase with analogues of pyrimethamine.

Birdsall B, Tendler SJ, Arnold JR, Feeney J, Griffin RJ, Carr MD, Thomas JA, Roberts GC, Stevens MF. Birdsall B, et al. Among authors: carr md. Biochemistry. 1990 Oct 16;29(41):9660-7. doi: 10.1021/bi00493a022. Biochemistry. 1990. PMID: 2125479

3

NMR assignment of the mTOR domain responsible for rapamycin binding.

Veverka V, Lennie G, Crabbe T, Bird I, Taylor RJ, Carr MD. Veverka V, et al. Among authors: carr md. J Biomol NMR. 2006;36 Suppl 1:3. doi: 10.1007/s10858-005-4324-1. J Biomol NMR. 2006. PMID: 16456707 No abstract available.

4

Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A.

Waters LC, Veverka V, Böhm M, Schmedt T, Choong PT, Muskett FW, Klempnauer KH, Carr MD. Waters LC, et al. Among authors: carr md. Oncogene. 2007 Jul 26;26(34):4941-50. doi: 10.1038/sj.onc.1210305. Epub 2007 Feb 19. Oncogene. 2007. PMID: 17310995

5

Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.

Veverka V, Crabbe T, Bird I, Lennie G, Muskett FW, Taylor RJ, Carr MD. Veverka V, et al. Among authors: carr md. Oncogene. 2008 Jan 24;27(5):585-95. doi: 10.1038/sj.onc.1210693. Epub 2007 Aug 6. Oncogene. 2008. PMID: 17684489

6

Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins.

Lightbody KL, Ilghari D, Waters LC, Carey G, Bailey MA, Williamson RA, Renshaw PS, Carr MD. Lightbody KL, et al. Among authors: carr md. J Biol Chem. 2008 Jun 20;283(25):17681-90. doi: 10.1074/jbc.M800123200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18430736 Free article.

7

Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation.

Veverka V, Henry AJ, Slocombe PM, Ventom A, Mulloy B, Muskett FW, Muzylak M, Greenslade K, Moore A, Zhang L, Gong J, Qian X, Paszty C, Taylor RJ, Robinson MK, Carr MD. Veverka V, et al. Among authors: carr md. J Biol Chem. 2009 Apr 17;284(16):10890-900. doi: 10.1074/jbc.M807994200. Epub 2009 Feb 10. J Biol Chem. 2009. PMID: 19208630 Free PMC article.

8

High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development.

Wilkinson IC, Hall CJ, Veverka V, Shi JY, Muskett FW, Stephens PE, Taylor RJ, Henry AJ, Carr MD. Wilkinson IC, et al. Among authors: carr md. J Biol Chem. 2009 Nov 13;284(46):31928-35. doi: 10.1074/jbc.M109.025304. Epub 2009 Sep 23. J Biol Chem. 2009. PMID: 19776018 Free PMC article.

9

(15)N, (13)C and (1)H resonance assignments and secondary structure determination of the Mycobacterium tuberculosis Rv0287-Rv0288 protein complex.

Ilghari D, Waters LC, Veverka V, Muskett FW, Carr MD. Ilghari D, et al. Among authors: carr md. Biomol NMR Assign. 2009 Dec;3(2):171-4. doi: 10.1007/s12104-009-9167-3. Epub 2009 Jun 21. Biomol NMR Assign. 2009. PMID: 19888683

10

Resonance assignment and secondary structure of the middle MA-3 domain and complete tandem MA-3 region of the tumour suppressor protein Pdcd4.

Waters LC, Oka O, Muskett FW, Strong SL, Schmedt T, Klempnauer KH, Carr MD. Waters LC, et al. Among authors: carr md. Biomol NMR Assign. 2010 Apr;4(1):49-53. doi: 10.1007/s12104-009-9205-1. Epub 2009 Dec 19. Biomol NMR Assign. 2010. PMID: 20020227 Free PMC article.

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