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Thalidomide mimics uridine binding to an aromatic cage in cereblon.
Hartmann MD, Boichenko I, Coles M, Zanini F, Lupas AN, Hernandez Alvarez B. Hartmann MD, et al. Among authors: boichenko i. J Struct Biol. 2014 Dec;188(3):225-32. doi: 10.1016/j.jsb.2014.10.010. Epub 2014 Nov 4. J Struct Biol. 2014. PMID: 25448889 Free article.
Structural dynamics of the cereblon ligand binding domain.
Hartmann MD, Boichenko I, Coles M, Lupas AN, Hernandez Alvarez B. Hartmann MD, et al. Among authors: boichenko i. PLoS One. 2015 May 29;10(5):e0128342. doi: 10.1371/journal.pone.0128342. eCollection 2015. PLoS One. 2015. PMID: 26024445 Free PMC article.
Chemical Ligand Space of Cereblon.
Boichenko I, Bär K, Deiss S, Heim C, Albrecht R, Lupas AN, Hernandez Alvarez B, Hartmann MD. Boichenko I, et al. ACS Omega. 2018 Sep 14;3(9):11163-11171. doi: 10.1021/acsomega.8b00959. eCollection 2018 Sep 30. ACS Omega. 2018. PMID: 31459225 Free PMC article.
13 results