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Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.
Moghaddas F, Zeng P, Zhang Y, Schützle H, Brenner S, Hofmann SR, Berner R, Zhao Y, Lu B, Chen X, Zhang L, Cheng S, Winkler S, Lehmberg K, Canna SW, Czabotar PE, Wicks IP, De Nardo D, Hedrich CM, Zeng H, Masters SL. Moghaddas F, et al. Among authors: winkler s. J Allergy Clin Immunol. 2018 Dec;142(6):1956-1967.e6. doi: 10.1016/j.jaci.2018.04.033. Epub 2018 May 17. J Allergy Clin Immunol. 2018. PMID: 29778503 Free PMC article.
Interference of canakinumab with commercial IL-1β ELISAs.
Linge M, Hedrich CM, Rösen-Wolff A, Winkler S. Linge M, et al. Among authors: winkler s. Clin Immunol. 2019 Aug;205:6-7. doi: 10.1016/j.clim.2019.05.008. Epub 2019 May 13. Clin Immunol. 2019. PMID: 31096037 No abstract available.
CASP1 variants influence subcellular caspase-1 localization, pyroptosome formation, pro-inflammatory cell death and macrophage deformability.
Kapplusch F, Schulze F, Rabe-Matschewsky S, Russ S, Herbig M, Heymann MC, Schoepf K, Stein R, Range U, Rösen-Wolff A, Winkler S, Hedrich CM, Guck J, Hofmann SR. Kapplusch F, et al. Among authors: winkler s. Clin Immunol. 2019 Nov;208:108232. doi: 10.1016/j.clim.2019.06.008. Epub 2019 Jun 26. Clin Immunol. 2019. PMID: 31252176
Human procaspase-1 variants with decreased enzymatic activity are associated with febrile episodes and may contribute to inflammation via RIP2 and NF-κB signaling.
Heymann MC, Winkler S, Luksch H, Flecks S, Franke M, Ruß S, Ozen S, Yilmaz E, Klein C, Kallinich T, Lindemann D, Brenner S, Ganser G, Roesler J, Rösen-Wolff A, Hofmann SR. Heymann MC, et al. Among authors: winkler s. J Immunol. 2014 May 1;192(9):4379-85. doi: 10.4049/jimmunol.1203524. Epub 2014 Apr 4. J Immunol. 2014. PMID: 24706726
Janus kinase inhibition in complement component 1 deficiency.
Wolf C, Brück N, Koss S, Griep C, Kirschfink M, Palm-Beden K, Fang M, Röber N, Winkler S, Berner R, Latz E, Günther C, Lee-Kirsch MA. Wolf C, et al. Among authors: winkler s. J Allergy Clin Immunol. 2020 Dec;146(6):1439-1442.e5. doi: 10.1016/j.jaci.2020.04.002. Epub 2020 Apr 20. J Allergy Clin Immunol. 2020. PMID: 32325142 Free article. No abstract available.
842 results