Orwenyo J - Search Results

1

Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.

Trastoy B, Klontz E, Orwenyo J, Marina A, Wang LX, Sundberg EJ, Guerin ME. Trastoy B, et al. Among authors: orwenyo j. Nat Commun. 2018 May 14;9(1):1874. doi: 10.1038/s41467-018-04300-x. Nat Commun. 2018. PMID: 29760474 Free PMC article.

2

Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2.

Klontz EH, Trastoy B, Deredge D, Fields JK, Li C, Orwenyo J, Marina A, Beadenkopf R, Günther S, Flores J, Wintrode PL, Wang LX, Guerin ME, Sundberg EJ. Klontz EH, et al. Among authors: orwenyo j. ACS Cent Sci. 2019 Mar 27;5(3):524-538. doi: 10.1021/acscentsci.8b00917. Epub 2019 Feb 6. ACS Cent Sci. 2019. PMID: 30937380 Free PMC article.

3

Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein.

Orwenyo J, Huang W, Wang LX. Orwenyo J, et al. Bioorg Med Chem. 2013 Aug 15;21(16):4768-77. doi: 10.1016/j.bmc.2013.03.009. Epub 2013 Mar 21. Bioorg Med Chem. 2013. PMID: 23566760 Free PMC article.

4

One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes.

Tong X, Li T, Orwenyo J, Toonstra C, Wang LX. Tong X, et al. Among authors: orwenyo j. Bioorg Med Chem. 2018 Apr 1;26(7):1347-1355. doi: 10.1016/j.bmc.2017.07.053. Epub 2017 Jul 29. Bioorg Med Chem. 2018. PMID: 28789910 Free PMC article.

5

Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies.

Amin MN, McLellan JS, Huang W, Orwenyo J, Burton DR, Koff WC, Kwong PD, Wang LX. Amin MN, et al. Among authors: orwenyo j. Nat Chem Biol. 2013 Aug;9(8):521-6. doi: 10.1038/nchembio.1288. Epub 2013 Jun 30. Nat Chem Biol. 2013. PMID: 23831758 Free PMC article.

6

A two-step enzymatic glycosylation of polypeptides with complex N-glycans.

Lomino JV, Naegeli A, Orwenyo J, Amin MN, Aebi M, Wang LX. Lomino JV, et al. Among authors: orwenyo j. Bioorg Med Chem. 2013 Apr 15;21(8):2262-2270. doi: 10.1016/j.bmc.2013.02.007. Epub 2013 Feb 18. Bioorg Med Chem. 2013. PMID: 23477942 Free PMC article.

7

Systematic Synthesis and Binding Study of HIV V3 Glycopeptides Reveal the Fine Epitopes of Several Broadly Neutralizing Antibodies.

Orwenyo J, Cai H, Giddens J, Amin MN, Toonstra C, Wang LX. Orwenyo J, et al. ACS Chem Biol. 2017 Jun 16;12(6):1566-1575. doi: 10.1021/acschembio.7b00319. Epub 2017 Apr 28. ACS Chem Biol. 2017. PMID: 28414420 Free PMC article.

8

Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies.

Cai H, Orwenyo J, Guenaga J, Giddens J, Toonstra C, Wyatt RT, Wang LX. Cai H, et al. Among authors: orwenyo j. Chem Commun (Camb). 2017 May 14;53(39):5453-5456. doi: 10.1039/c7cc02059g. Epub 2017 May 3. Chem Commun (Camb). 2017. PMID: 28466900 Free PMC article.

9

The Odd "RB" Phage-Identification of Arabinosylation as a New Epigenetic Modification of DNA in T4-Like Phage RB69.

Thomas JA, Orwenyo J, Wang LX, Black LW. Thomas JA, et al. Among authors: orwenyo j. Viruses. 2018 Jun 8;10(6):313. doi: 10.3390/v10060313. Viruses. 2018. PMID: 29890699 Free PMC article.

10

Synthetic HIV V3 Glycopeptide Immunogen Carrying a N334 N-Glycan Induces Glycan-Dependent Antibodies with Promiscuous Site Recognition.

Cai H, Zhang RS, Orwenyo J, Giddens J, Yang Q, LaBranche CC, Montefiori DC, Wang LX. Cai H, et al. Among authors: orwenyo j. J Med Chem. 2018 Nov 21;61(22):10116-10125. doi: 10.1021/acs.jmedchem.8b01290. Epub 2018 Nov 8. J Med Chem. 2018. PMID: 30384610 Free PMC article.

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