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Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT.
Sci Adv. 2018 May 11;4(5):eaar6179. doi: 10.1126/sciadv.aar6179. eCollection 2018 May.
Sci Adv. 2018.
PMID: 29756037
Free PMC article.
Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS.
Möller IR, Merkle PS, Calugareanu D, Comamala G, Schmidt SG, Loland CJ, Rand KD.
Möller IR, et al. Among authors: merkle ps.
J Proteomics. 2020 Aug 15;225:103845. doi: 10.1016/j.jprot.2020.103845. Epub 2020 May 30.
J Proteomics. 2020.
PMID: 32480080
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The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β2-Microglobulin through Distinct Binding Sites.
Merkle PS, Irving M, Hongjian S, Ferber M, Jørgensen TJD, Scholten K, Luescher I, Coukos G, Zoete V, Cuendet MA, Michielin O, Rand KD.
Merkle PS, et al.
Biochemistry. 2017 Aug 1;56(30):3945-3961. doi: 10.1021/acs.biochem.7b00385. Epub 2017 Jul 19.
Biochemistry. 2017.
PMID: 28671821
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Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments.
Möller IR, Slivacka M, Hausner J, Nielsen AK, Pospíšilová E, Merkle PS, Lišková R, Polák M, Loland CJ, Kádek A, Man P, Rand KD.
Möller IR, et al. Among authors: merkle ps.
Anal Chem. 2019 Sep 3;91(17):10970-10978. doi: 10.1021/acs.analchem.9b00973. Epub 2019 Aug 13.
Anal Chem. 2019.
PMID: 31408320
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Probing the Conformational Dynamics of Affinity-Enhanced T Cell Receptor Variants upon Binding the Peptide-Bound Major Histocompatibility Complex by Hydrogen/Deuterium Exchange Mass Spectrometry.
Merkle PS, Trabjerg E, Hongjian S, Ferber M, Cuendet MA, Jørgensen TJD, Luescher I, Irving M, Zoete V, Michielin O, Rand KD.
Merkle PS, et al.
Biochemistry. 2021 Mar 23;60(11):859-872. doi: 10.1021/acs.biochem.1c00035. Epub 2021 Mar 9.
Biochemistry. 2021.
PMID: 33689297
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