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Generation of three-dimensional human neuronal cultures: application to modeling CNS viral infections.
D'Aiuto L, Naciri J, Radio N, Tekur S, Clayton D, Apodaca G, Di Maio R, Zhi Y, Dimitrion P, Piazza P, Demers M, Wood J, Chu C, Callio J, McClain L, Yolken R, McNulty J, Kinchington P, Bloom D, Nimgaonkar V. D'Aiuto L, et al. Among authors: mcclain l. Stem Cell Res Ther. 2018 May 11;9(1):134. doi: 10.1186/s13287-018-0881-6. Stem Cell Res Ther. 2018. PMID: 29751846 Free PMC article.
Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation.
D'Aiuto L, Zhi Y, Kumar Das D, Wilcox MR, Johnson JW, McClain L, MacDonald ML, Di Maio R, Schurdak ME, Piazza P, Viggiano L, Sweet R, Kinchington PR, Bhattacharjee AG, Yolken R, Nimgaonkar VL. D'Aiuto L, et al. Among authors: mcclain l. Organogenesis. 2014;10(4):365-77. doi: 10.1080/15476278.2015.1011921. Organogenesis. 2014. PMID: 25629202 Free PMC article.
Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells.
D'Aiuto L, Bloom DC, Naciri JN, Smith A, Edwards TG, McClain L, Callio JA, Jessup M, Wood J, Chowdari K, Demers M, Abrahamson EE, Ikonomovic MD, Viggiano L, De Zio R, Watkins S, Kinchington PR, Nimgaonkar VL. D'Aiuto L, et al. Among authors: mcclain l. J Virol. 2019 Apr 17;93(9):e00111-19. doi: 10.1128/JVI.00111-19. Print 2019 May 1. J Virol. 2019. PMID: 30787148 Free PMC article.
Broad-spectrum non-nucleoside inhibitors of human herpesviruses.
McClain L, Zhi Y, Cheng H, Ghosh A, Piazza P, Yee MB, Kumar S, Milosevic J, Bloom DC, Arav-Boger R, Kinchington PR, Yolken R, Nimgaonkar V, D'Aiuto L. McClain L, et al. Antiviral Res. 2015 Sep;121:16-23. doi: 10.1016/j.antiviral.2015.06.005. Epub 2015 Jun 12. Antiviral Res. 2015. PMID: 26079681 Free PMC article.
iPSC Neuronal Assay Identifies Amaryllidaceae Pharmacophore with Multiple Effects against Herpesvirus Infections.
McNulty J, D'Aiuto L, Zhi Y, McClain L, Zepeda-Velázquez C, Ler S, Jenkins HA, Yee MB, Piazza P, Yolken RH, Kinchington PR, Nimgaonkar VL. McNulty J, et al. Among authors: mcclain l. ACS Med Chem Lett. 2015 Nov 19;7(1):46-50. doi: 10.1021/acsmedchemlett.5b00318. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819664 Free PMC article.
R430: A potent inhibitor of DNA and RNA viruses.
D'Aiuto L, McNulty J, Hartline C, Demers M, Kalkeri R, Wood J, McClain L, Chattopadhyay A, Zhi Y, Naciri J, Smith A, Yolken R, Chowdari K, Zepeda-Velazquez C, Dokuburra CB, Marques E, Ptak R, Kinchington P, Watkins S, Prichard M, Bloom D, Nimgaonkar V. D'Aiuto L, et al. Among authors: mcclain l. Sci Rep. 2018 Nov 9;8(1):16662. doi: 10.1038/s41598-018-33904-y. Sci Rep. 2018. PMID: 30413769 Free PMC article.
Persistent infection by HSV-1 is associated with changes in functional architecture of iPSC-derived neurons and brain activation patterns underlying working memory performance.
D'Aiuto L, Prasad KM, Upton CH, Viggiano L, Milosevic J, Raimondi G, McClain L, Chowdari K, Tischfield J, Sheldon M, Moore JC, Yolken RH, Kinchington PR, Nimgaonkar VL. D'Aiuto L, et al. Among authors: mcclain l. Schizophr Bull. 2015 Jan;41(1):123-32. doi: 10.1093/schbul/sbu032. Epub 2014 Mar 12. Schizophr Bull. 2015. PMID: 24622295 Free PMC article.
108 results