Hart SL - Search Results

1

Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.

Tagalakis AD, Munye MM, Ivanova R, Chen H, Smith CM, Aldossary AM, Rosa LZ, Moulding D, Barnes JL, Kafetzis KN, Jones SA, Baines DL, Moss GWJ, O'Callaghan C, McAnulty RJ, Hart SL. Tagalakis AD, et al. Among authors: hart sl. Thorax. 2018 Sep;73(9):847-856. doi: 10.1136/thoraxjnl-2017-210670. Epub 2018 May 10. Thorax. 2018. PMID: 29748250 Free PMC article.

2

An integrin-targeted non-viral vector for pulmonary gene therapy.

Jenkins RG, Herrick SE, Meng QH, Kinnon C, Laurent GJ, McAnulty RJ, Hart SL. Jenkins RG, et al. Among authors: hart sl. Gene Ther. 2000 Mar;7(5):393-400. doi: 10.1038/sj.gt.3301095. Gene Ther. 2000. PMID: 10694821

3

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice.

Keerthisingam CB, Jenkins RG, Harrison NK, Hernandez-Rodriguez NA, Booth H, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Keerthisingam CB, et al. Among authors: hart sl. Am J Pathol. 2001 Apr;158(4):1411-22. doi: 10.1016/s0002-9440(10)64092-8. Am J Pathol. 2001. PMID: 11290559 Free PMC article.

4

Cyclooxygenase-2 overexpression, using an integrin-targeted gene delivery system (the LID vector), inhibits fibroblast proliferation in vitro and leads to increased prostaglandin E(2) in the lung.

Jenkins G, Hart SL, Hodges RJ, Meng QH, Kinnon C, Laurent GJ, McAnulty RJ. Jenkins G, et al. Among authors: hart sl. Chest. 2002 Mar;121(3 Suppl):102S-104S. doi: 10.1378/chest.121.3_suppl.102s. Chest. 2002. PMID: 11893724 No abstract available.

5

Evaluation of a porcine model for pulmonary gene transfer using a novel synthetic vector.

Cunningham S, Meng QH, Klein N, McAnulty RJ, Hart SL. Cunningham S, et al. Among authors: hart sl. J Gene Med. 2002 Jul-Aug;4(4):438-46. doi: 10.1002/jgm.270. J Gene Med. 2002. PMID: 12124986

6

Biophysical characterization of an integrin-targeted non-viral vector.

Lee LK, Siapati EK, Jenkins RG, McAnulty RJ, Hart SL, Shamlou PA. Lee LK, et al. Among authors: hart sl. Med Sci Monit. 2003 Jan;9(1):BR54-61. Med Sci Monit. 2003. PMID: 12552238

7

Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo.

Jenkins RG, Meng QH, Hodges RJ, Lee LK, Bottoms SE, Laurent GJ, Willis D, Ayazi Shamlou P, McAnulty RJ, Hart SL. Jenkins RG, et al. Among authors: hart sl. Gene Ther. 2003 Jun;10(12):1026-34. doi: 10.1038/sj.gt.3301963. Gene Ther. 2003. PMID: 12776160

8

Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land?

Jenkins RG, McAnulty RJ, Hart SL, Laurent GJ. Jenkins RG, et al. Among authors: hart sl. Monaldi Arch Chest Dis. 2003 Jan-Mar;59(1):17-24. Monaldi Arch Chest Dis. 2003. PMID: 14533278 Review.

9

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

Meng QH, Robinson D, Jenkins RG, McAnulty RJ, Hart SL. Meng QH, et al. Among authors: hart sl. J Gene Med. 2004 Feb;6(2):210-21. doi: 10.1002/jgm.483. J Gene Med. 2004. PMID: 14978774

10

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

Hodges RJ, Jenkins RG, Wheeler-Jones CP, Copeman DM, Bottoms SE, Bellingan GJ, Nanthakumar CB, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Hodges RJ, et al. Among authors: hart sl. Am J Pathol. 2004 Nov;165(5):1663-76. doi: 10.1016/S0002-9440(10)63423-2. Am J Pathol. 2004. PMID: 15509536 Free PMC article.

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