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Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer.
Russo Spena C, De Stefano L, Palazzolo S, Salis B, Granchi C, Minutolo F, Tuccinardi T, Fratamico R, Crotti S, D'Aronco S, Agostini M, Corona G, Caligiuri I, Canzonieri V, Rizzolio F. Russo Spena C, et al. Among authors: granchi c. J Control Release. 2018 Jul 10;281:1-10. doi: 10.1016/j.jconrel.2018.04.055. Epub 2018 May 8. J Control Release. 2018. PMID: 29746956 Free article.
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Granchi C, Roy S, Giacomelli C, Macchia M, Tuccinardi T, Martinelli A, Lanza M, Betti L, Giannaccini G, Lucacchini A, Funel N, León LG, Giovannetti E, Peters GJ, Palchaudhuri R, Calvaresi EC, Hergenrother PJ, Minutolo F. Granchi C, et al. J Med Chem. 2011 Mar 24;54(6):1599-612. doi: 10.1021/jm101007q. Epub 2011 Feb 18. J Med Chem. 2011. PMID: 21332213
Anticancer agents that counteract tumor glycolysis.
Granchi C, Minutolo F. Granchi C, et al. ChemMedChem. 2012 Aug;7(8):1318-50. doi: 10.1002/cmdc.201200176. Epub 2012 Jun 8. ChemMedChem. 2012. PMID: 22684868 Free PMC article. Review.
109 results