Tomic MT - Search Results

1

An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E.

Li M, Lee D, Obi CR, Freeberg JK, Farr-Jones S, Tomic MT. Li M, et al. Among authors: tomic mt. PLoS One. 2018 May 10;13(5):e0197011. doi: 10.1371/journal.pone.0197011. eCollection 2018. PLoS One. 2018. PMID: 29746518 Free PMC article.

2

Separation of oxidized variants of a monoclonal antibody by anion-exchange.

Teshima G, Li MX, Danishmand R, Obi C, To R, Huang C, Kung J, Lahidji V, Freeberg J, Thorner L, Tomic M. Teshima G, et al. J Chromatogr A. 2011 Apr 15;1218(15):2091-7. doi: 10.1016/j.chroma.2010.10.107. Epub 2010 Nov 16. J Chromatogr A. 2011. PMID: 21145555 Free PMC article.

3

Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model.

Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD. Tomic MT, et al. Toxins (Basel). 2019 Apr 6;11(4):208. doi: 10.3390/toxins11040208. Toxins (Basel). 2019. PMID: 30959899 Free PMC article.

4

Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats.

Espinoza Y, Wong D, Ahene A, Der K, Martinez Z, Pham J, Cobb RR, Farr-Jones S, Marks JD, Tomic MT. Espinoza Y, et al. Among authors: tomic mt. Toxins (Basel). 2019 Jun 17;11(6):345. doi: 10.3390/toxins11060345. Toxins (Basel). 2019. PMID: 31212950 Free PMC article.

5

A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model.

Snow DM, Cobb RR, Martinez J, Finger-Baker I, Collins L, Terpening S, Syar ES, Niemuth N, Kobs D, Barnewall R, Farr-Jones S, Marks JD, Tomic MT. Snow DM, et al. Among authors: tomic mt. Toxins (Basel). 2021 Jan 5;13(1):31. doi: 10.3390/toxins13010031. Toxins (Basel). 2021. PMID: 33466411 Free PMC article.

6

Neutralizing Concentrations of Anti-Botulinum Toxin Antibodies Positively Correlate with Mouse Neutralization Assay Results in a Guinea Pig Model.

Tomic MT, Farr-Jones S, Syar ES, Niemuth N, Kobs D, Hackett MJ, Espinoza Y, Martinez Z, Pham K, Snow DM, Marks JD, Cobb RR. Tomic MT, et al. Toxins (Basel). 2021 Sep 21;13(9):671. doi: 10.3390/toxins13090671. Toxins (Basel). 2021. PMID: 34564675 Free PMC article.

7

Engineered domain-based assays to identify individual antibodies in oligoclonal combinations targeting the same protein.

Meng Q, Garcia-Rodriguez C, Manzanarez G, Silberg MA, Conrad F, Bettencourt J, Pan X, Breece T, To R, Li M, Lee D, Thorner L, Tomic MT, Marks JD. Meng Q, et al. Among authors: tomic mt. Anal Biochem. 2012 Nov 15;430(2):141-50. doi: 10.1016/j.ab.2012.08.005. Epub 2012 Aug 21. Anal Biochem. 2012. PMID: 22922799 Free PMC article.

8

Domain-based assays of individual antibody concentrations in an oligoclonal combination targeting a single protein.

Meng Q, Li M, Silberg MA, Conrad F, Bettencourt J, To R, Huang C, Ma J, Meyer K, Shimizu R, Cao L, Tomic MT, Marks JD. Meng Q, et al. Among authors: tomic mt. Anal Biochem. 2012 Feb 15;421(2):351-61. doi: 10.1016/j.ab.2011.09.030. Epub 2011 Oct 6. Anal Biochem. 2012. PMID: 22037290 Free PMC article.

9

Antibody engineering to improve manufacturability.

Wijesuriya SD, Pongo E, Tomic M, Zhang F, Garcia-Rodriquez C, Conrad F, Farr-Jones S, Marks JD, Horwitz AH. Wijesuriya SD, et al. Protein Expr Purif. 2018 Sep;149:75-83. doi: 10.1016/j.pep.2018.04.003. Epub 2018 Apr 12. Protein Expr Purif. 2018. PMID: 29655788

10

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin.

Garcia-Rodriguez C, Geren IN, Lou J, Conrad F, Forsyth C, Wen W, Chakraborti S, Zao H, Manzanarez G, Smith TJ, Brown J, Tepp WH, Liu N, Wijesuriya S, Tomic MT, Johnson EA, Smith LA, Marks JD. Garcia-Rodriguez C, et al. Among authors: tomic mt. Protein Eng Des Sel. 2011 Mar;24(3):321-31. doi: 10.1093/protein/gzq111. Epub 2010 Dec 13. Protein Eng Des Sel. 2011. PMID: 21149386 Free PMC article.

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