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Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.
Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M. Fang R, et al. Among authors: shen y. J Immunol. 2011 Nov 1;187(9):4890-9. doi: 10.4049/jimmunol.1100381. Epub 2011 Sep 28. J Immunol. 2011. PMID: 21957143 Free PMC article.
The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL-1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation.
Yang R, Xi C, Sita DR, Sakai S, Tsuchiya K, Hara H, Shen Y, Qu H, Fang R, Mitsuyama M, Kawamura I. Yang R, et al. Among authors: shen y. Pathog Dis. 2014 Feb;70(1):51-60. doi: 10.1111/2049-632X.12075. Epub 2013 Aug 23. Pathog Dis. 2014. PMID: 23913588
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