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A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma.
Clin Cancer Res. 2018 Aug 1;24(15):3611-3631. doi: 10.1158/1078-0432.CCR-17-0126. Epub 2018 Apr 27.
Clin Cancer Res. 2018.
PMID: 29703821
Free PMC article.
MRP3: a molecular target for human glioblastoma multiforme immunotherapy.
Kuan CT, Wakiya K, Herndon JE 2nd, Lipp ES, Pegram CN, Riggins GJ, Rasheed A, Szafranski SE, McLendon RE, Wikstrand CJ, Bigner DD.
Kuan CT, et al. Among authors: szafranski se.
BMC Cancer. 2010 Sep 1;10:468. doi: 10.1186/1471-2407-10-468.
BMC Cancer. 2010.
PMID: 20809959
Free PMC article.
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Recombinant anti-podoplanin (NZ-1) immunotoxin for the treatment of malignant brain tumors.
Chandramohan V, Bao X, Kato Kaneko M, Kato Y, Keir ST, Szafranski SE, Kuan CT, Pastan IH, Bigner DD.
Chandramohan V, et al. Among authors: szafranski se.
Int J Cancer. 2013 May 15;132(10):2339-48. doi: 10.1002/ijc.27919. Epub 2012 Nov 23.
Int J Cancer. 2013.
PMID: 23115013
Free PMC article.
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Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.
Chandramohan V, Bao X, Keir ST, Pegram CN, Szafranski SE, Piao H, Wikstrand CJ, McLendon RE, Kuan CT, Pastan IH, Bigner DD.
Chandramohan V, et al. Among authors: szafranski se.
Clin Cancer Res. 2013 Sep 1;19(17):4717-27. doi: 10.1158/1078-0432.CCR-12-3891. Epub 2013 Jul 15.
Clin Cancer Res. 2013.
PMID: 23857604
Free PMC article.
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Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial.
Chandramohan V, Pegram CN, Piao H, Szafranski SE, Kuan CT, Pastan IH, Bigner DD.
Chandramohan V, et al. Among authors: szafranski se.
Appl Microbiol Biotechnol. 2017 Apr;101(7):2747-2766. doi: 10.1007/s00253-016-8063-x. Epub 2016 Dec 24.
Appl Microbiol Biotechnol. 2017.
PMID: 28013405
Free PMC article.
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