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Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.
Zheng YC, Duan YC, Ma JL, Xu RM, Zi X, Lv WL, Wang MM, Ye XW, Zhu S, Mobley D, Zhu YY, Wang JW, Li JF, Wang ZR, Zhao W, Liu HM. Zheng YC, et al. Among authors: wang jw, wang mm, wang zr. J Med Chem. 2013 Nov 14;56(21):8543-60. doi: 10.1021/jm401002r. Epub 2013 Nov 1. J Med Chem. 2013. PMID: 24131029 Free PMC article.
Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.
Ma LY, Zheng YC, Wang SQ, Wang B, Wang ZR, Pang LP, Zhang M, Wang JW, Ding L, Li J, Wang C, Hu B, Liu Y, Zhang XD, Wang JJ, Wang ZJ, Zhao W, Liu HM. Ma LY, et al. Among authors: wang sq, wang jw, wang jj, wang zj, wang zr, wang c, wang b. J Med Chem. 2015 Feb 26;58(4):1705-16. doi: 10.1021/acs.jmedchem.5b00037. Epub 2015 Feb 6. J Med Chem. 2015. PMID: 25610955
1,980 results