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EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition.
Sato F, Kubota Y, Natsuizaka M, Maehara O, Hatanaka Y, Marukawa K, Terashita K, Suda G, Ohnishi S, Shimizu Y, Komatsu Y, Ohashi S, Kagawa S, Kinugasa H, Whelan KA, Nakagawa H, Sakamoto N. Sato F, et al. Among authors: whelan ka. Cancer Biol Ther. 2015;16(6):933-40. doi: 10.1080/15384047.2015.1040959. Epub 2015 Apr 21. Cancer Biol Ther. 2015. PMID: 25897987 Free PMC article.
Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis.
Whelan KA, Merves JF, Giroux V, Tanaka K, Guo A, Chandramouleeswaran PM, Benitez AJ, Dods K, Que J, Masterson JC, Fernando SD, Godwin BC, Klein-Szanto AJ, Chikwava K, Ruchelli ED, Hamilton KE, Muir AB, Wang ML, Furuta GT, Falk GW, Spergel JM, Nakagawa H. Whelan KA, et al. Gut. 2017 Jul;66(7):1197-1207. doi: 10.1136/gutjnl-2015-310341. Epub 2016 Feb 16. Gut. 2017. PMID: 26884425 Free PMC article.
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, Wang TC, Rustgi AK. Giroux V, et al. Among authors: whelan ka. J Clin Invest. 2017 Jun 1;127(6):2378-2391. doi: 10.1172/JCI88941. Epub 2017 May 8. J Clin Invest. 2017. PMID: 28481227 Free PMC article.
Fibroblast growth factor-2-mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma.
Maehara O, Suda G, Natsuizaka M, Ohnishi S, Komatsu Y, Sato F, Nakai M, Sho T, Morikawa K, Ogawa K, Shimazaki T, Kimura M, Asano A, Fujimoto Y, Ohashi S, Kagawa S, Kinugasa H, Naganuma S, Whelan KA, Nakagawa H, Nakagawa K, Takeda H, Sakamoto N. Maehara O, et al. Among authors: whelan ka. Carcinogenesis. 2017 Oct 26;38(11):1073-1083. doi: 10.1093/carcin/bgx095. Carcinogenesis. 2017. PMID: 28927233 Free PMC article.
The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes.
Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, Muir AB, Nakagawa H. Kasagi Y, et al. Among authors: whelan ka. Cell Mol Gastroenterol Hepatol. 2018 Jan 3;5(3):333-352. doi: 10.1016/j.jcmgh.2017.12.013. eCollection 2018 Mar. Cell Mol Gastroenterol Hepatol. 2018. PMID: 29552622 Free PMC article.
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.
Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, Shinden Y, Sasaki K, Omoto I, Kita Y, Muto M, Bass AJ, Diehl JA, Ginsberg GG, Doki Y, Mori M, Uchikado Y, Arigami T, Avadhani NG, Basu D, Rustgi AK, Natsugoe S. Kijima T, et al. Among authors: whelan ka. Cell Mol Gastroenterol Hepatol. 2018 Sep 14;7(1):73-91. doi: 10.1016/j.jcmgh.2018.09.003. eCollection 2019. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30510992 Free PMC article.
RNA regulons are essential in intestinal homeostasis.
Parham LR, Williams PA, Chatterji P, Whelan KA, Hamilton KE. Parham LR, et al. Among authors: whelan ka. Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G197-G204. doi: 10.1152/ajpgi.00403.2017. Epub 2018 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30520692 Free PMC article. Review.
75 results