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CRISPR/Cas9 for cancer research and therapy.
Zhan T, Rindtorff N, Betge J, Ebert MP, Boutros M. Zhan T, et al. Among authors: betge j. Semin Cancer Biol. 2019 Apr;55:106-119. doi: 10.1016/j.semcancer.2018.04.001. Epub 2018 Apr 16. Semin Cancer Biol. 2019. PMID: 29673923 Free article. Review.
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer.
Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler RS, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M. Zhan T, et al. Among authors: betge j. Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0. Nat Commun. 2019. PMID: 31097693 Free PMC article.
Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors.
Bamberg LV, Heigwer F, Wandmacher AM, Singh A, Betge J, Rindtorff N, Werner J, Josten J, Skabkina OV, Hinsenkamp I, Erdmann G, Röcken C, Ebert MP, Burgermeister E, Zhan T, Boutros M. Bamberg LV, et al. Among authors: betge j. Int J Cancer. 2022 Nov 1;151(9):1586-1601. doi: 10.1002/ijc.34155. Epub 2022 Jun 28. Int J Cancer. 2022. PMID: 35666536 Free article.
Personalized functional profiling using ex-vivo patient-derived spheroids points out the potential of an antiangiogenic treatment in a patient with a metastatic lung atypical carcinoid.
Kim H, El-Khoury V, Schulte N, Zhan T, Betge J, Cousin L, Felli E, Pessaux P, Ogier A, Opitz O, Ku B, Ebert MP, Kwon YJ. Kim H, et al. Among authors: betge j. Cancer Biol Ther. 2022 Dec 31;23(1):96-102. doi: 10.1080/15384047.2021.2021042. Cancer Biol Ther. 2022. PMID: 35193475 Free PMC article.
The drug-induced phenotypic landscape of colorectal cancer organoids.
Betge J, Rindtorff N, Sauer J, Rauscher B, Dingert C, Gaitantzi H, Herweck F, Srour-Mhanna K, Miersch T, Valentini E, Boonekamp KE, Hauber V, Gutting T, Frank L, Belle S, Gaiser T, Buchholz I, Jesenofsky R, Härtel N, Zhan T, Fischer B, Breitkopf-Heinlein K, Burgermeister E, Ebert MP, Boutros M. Betge J, et al. Nat Commun. 2022 Jun 6;13(1):3135. doi: 10.1038/s41467-022-30722-9. Nat Commun. 2022. PMID: 35668108 Free PMC article.
A multicenter open-label phase II trial to evaluate nivolumab and ipilimumab for 2nd line therapy in elderly patients with advanced esophageal squamous cell cancer (RAMONA).
Meindl-Beinker NM, Betge J, Gutting T, Burgermeister E, Belle S, Zhan T, Schulte N, Maenz M, Ebert MP, Haertel N. Meindl-Beinker NM, et al. Among authors: betge j. BMC Cancer. 2019 Mar 14;19(1):231. doi: 10.1186/s12885-019-5446-2. BMC Cancer. 2019. PMID: 30871493 Free PMC article. Clinical Trial.
48 results