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Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein.
Velázquez-López I, Valdés-García G, Romero Romero S, Maya Martínez R, Leal-Cervantes AI, Costas M, Sánchez-López R, Amero C, Pastor N, Fernández Velasco DA. Velázquez-López I, et al. Among authors: romero romero s. Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1656-1666. doi: 10.1016/j.bbagen.2018.04.014. Epub 2018 Apr 15. Biochim Biophys Acta Gen Subj. 2018. PMID: 29669263
A strategy based on thermal flexibility to design triosephosphate isomerase proteins with increased or decreased kinetic stability.
Quezada AG, Cabrera N, Piñeiro Á, Díaz-Salazar AJ, Díaz-Mazariegos S, Romero-Romero S, Pérez-Montfort R, Costas M. Quezada AG, et al. Among authors: romero romero s. Biochem Biophys Res Commun. 2018 Sep 18;503(4):3017-3022. doi: 10.1016/j.bbrc.2018.08.087. Epub 2018 Aug 22. Biochem Biophys Res Commun. 2018. PMID: 30143261
Structural basis for the modulation of plant cytosolic triosephosphate isomerase activity by mimicry of redox-based modifications.
Castro-Torres E, Jiménez-Sandoval P, Romero-Romero S, Fuentes-Pascacio A, López-Castillo LM, Díaz-Quezada C, Fernández-Velasco DA, Torres-Larios A, Brieba LG. Castro-Torres E, et al. Among authors: romero romero s. Plant J. 2019 Sep;99(5):950-964. doi: 10.1111/tpj.14375. Epub 2019 Jun 13. Plant J. 2019. PMID: 31034710 Free article.
FRET-based analysis and molecular modeling of the human GPN-loop GTPases 1 and 3 heterodimer unveils a dominant-negative protein complex.
Cristóbal-Mondragón GR, Lara-Chacón B, Santiago Á, De-la-Rosa V, González-González R, Muñiz-Luna JA, Ladrón-de-Guevara E, Romero-Romero S, Rangel-Yescas GE, Fernández Velasco DA, Islas LD, Pastor N, Sánchez-Olea R, Calera MR. Cristóbal-Mondragón GR, et al. Among authors: romero romero s. FEBS J. 2019 Dec;286(23):4797-4818. doi: 10.1111/febs.14996. Epub 2019 Jul 22. FEBS J. 2019. PMID: 31298811 Free article.
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
Romero-Romero S, Costas M, Silva Manzano DA, Kordes S, Rojas-Ortega E, Tapia C, Guerra Y, Shanmugaratnam S, Rodríguez-Romero A, Baker D, Höcker B, Fernández-Velasco DA. Romero-Romero S, et al. J Mol Biol. 2021 Sep 3;433(18):167153. doi: 10.1016/j.jmb.2021.167153. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271011 Free PMC article.
Thermodynamic and kinetic analysis of the LAO binding protein and its isolated domains reveal non-additivity in stability, folding and function.
Vergara R, Berrocal T, Juárez Mejía EI, Romero-Romero S, Velázquez-López I, Pulido NO, López Sanchez HA, Silva DA, Costas M, Rodríguez-Romero A, Rodríguez-Sotres R, Sosa-Peinado A, Fernández-Velasco DA. Vergara R, et al. Among authors: romero romero s. FEBS J. 2023 Sep;290(18):4496-4512. doi: 10.1111/febs.16819. Epub 2023 May 29. FEBS J. 2023. PMID: 37178351
27 results