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Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis.
Silva MC, Davoli-Ferreira M, Medina TS, Sesti-Costa R, Silva GK, Lopes CD, Cardozo LE, Gava FN, Lyroni K, Dias FC, Frade AF, Baron M, Nakaya HI, Figueiredo F, Alves-Filho JC, Cunha FQ, Tsatsanis C, Chevillard C, Cunha-Neto E, Hirsch E, Silva JS, Cunha TM. Silva MC, et al. Among authors: lopes cd. Nat Commun. 2018 Apr 17;9(1):1513. doi: 10.1038/s41467-018-03986-3. Nat Commun. 2018. PMID: 29666415 Free PMC article.
Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection.
Fermino ML, Dias FC, Lopes CD, Souza MA, Cruz ÂK, Liu FT, Chammas R, Roque-Barreira MC, Rabinovich GA, Bernardes ES. Fermino ML, et al. Among authors: lopes cd. Eur J Immunol. 2013 Jul;43(7):1806-17. doi: 10.1002/eji.201343381. Epub 2013 May 17. Eur J Immunol. 2013. PMID: 23592449 Free article.
In vitro and in vivo trypanocidal activity of H2bdtc-loaded solid lipid nanoparticles.
Carneiro ZA, Maia PI, Sesti-Costa R, Lopes CD, Pereira TA, Milanezi CM, da Silva MA, Lopez RF, Silva JS, Deflon VM. Carneiro ZA, et al. Among authors: lopes cd. PLoS Negl Trop Dis. 2014 May 8;8(5):e2847. doi: 10.1371/journal.pntd.0002847. eCollection 2014 May. PLoS Negl Trop Dis. 2014. PMID: 24810753 Free PMC article.
Prolonged dipyridamole administration reduces myocardial perfusion defects in experimental chronic Chagas cardiomyopathy.
Tanaka DM, de Oliveira LFL, Marin-Neto JA, Romano MMD, de Carvalho EEV, de Barros Filho ACL, Ribeiro FFF, Cabeza JM, Lopes CD, Fabricio CG, Kesper N, Moreira HT, Wichert-Ana L, Schmidt A, Higuchi ML, Cunha-Neto E, Simões MV. Tanaka DM, et al. Among authors: lopes cd. J Nucl Cardiol. 2019 Oct;26(5):1569-1579. doi: 10.1007/s12350-018-1198-7. Epub 2018 Feb 1. J Nucl Cardiol. 2019. PMID: 29392628
Synthesis and 2D-QSAR studies of neolignan-based diaryl-tetrahydrofuran and -furan analogues with remarkable activity against Trypanosoma cruzi and assessment of the trypanothione reductase activity.
Hartmann AP, de Carvalho MR, Bernardes LSC, Moraes MH, de Melo EB, Lopes CD, Steindel M, da Silva JS, Carvalho I. Hartmann AP, et al. Among authors: lopes cd. Eur J Med Chem. 2017 Nov 10;140:187-199. doi: 10.1016/j.ejmech.2017.08.064. Epub 2017 Sep 4. Eur J Med Chem. 2017. PMID: 28926763
Organometallic Gold(III) Complex [Au(Hdamp)(L14)]+ (L1 = SNS-Donating Thiosemicarbazone) as a Candidate to New Formulations against Chagas Disease.
Lopes CD, Possato B, Gaspari APS, Oliveira RJ, Abram U, Almeida JPA, Rocho FDR, Leitão A, Montanari CA, Maia PIS, da Silva JS, de Albuquerque S, Carneiro ZA. Lopes CD, et al. ACS Infect Dis. 2019 Oct 11;5(10):1698-1707. doi: 10.1021/acsinfecdis.8b00284. Epub 2019 Aug 26. ACS Infect Dis. 2019. PMID: 31419384
In vitro anti-Trypanosoma cruzi activity of ternary copper(II) complexes and in vivo evaluation of the most promising complex.
Paixão DA, Lopes CD, Carneiro ZA, Sousa LM, de Oliveira LP, Lopes NP, Pivatto M, Chaves JDS, de Almeida MV, Ellena J, Moreira MB, Netto AVG, de Oliveira RJ, Guilardi S, de Albuquerque S, Guerra W. Paixão DA, et al. Among authors: lopes np, lopes cd. Biomed Pharmacother. 2019 Jan;109:157-166. doi: 10.1016/j.biopha.2018.10.057. Epub 2018 Nov 2. Biomed Pharmacother. 2019. PMID: 30396072 Free article.
58 results