Ruiz-Gómez G - Search Results

1

N^ε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.

Wodtke R, Hauser C, Ruiz-Gómez G, Jäckel E, Bauer D, Lohse M, Wong A, Pufe J, Ludwig FA, Fischer S, Hauser S, Greif D, Pisabarro MT, Pietzsch J, Pietsch M, Löser R. Wodtke R, et al. J Med Chem. 2018 May 24;61(10):4528-4560. doi: 10.1021/acs.jmedchem.8b00286. Epub 2018 May 10. J Med Chem. 2018. PMID: 29664627

2

Structure-activity relationships for substrate-based inhibitors of human complement factor B.

Ruiz-Gómez G, Lim J, Halili MA, Le GT, Madala PK, Abbenante G, Fairlie DP. Ruiz-Gómez G, et al. J Med Chem. 2009 Oct 8;52(19):6042-52. doi: 10.1021/jm900781m. J Med Chem. 2009. PMID: 19743866

3

Cyclopeptides containing the DEKS motif as conformationally restricted collagen telopeptide analogues: synthesis and conformational analysis.

Wodtke R, Ruiz-Gómez G, Kuchar M, Pisabarro MT, Novotná P, Urbanová M, Steinbach J, Pietzsch J, Löser R. Wodtke R, et al. Org Biomol Chem. 2015 Feb 14;13(6):1878-96. doi: 10.1039/c4ob02348j. Org Biomol Chem. 2015. PMID: 25503999

4

Rational Structure-Based Rescaffolding Approach to De Novo Design of Interleukin 10 (IL-10) Receptor-1 Mimetics.

Ruiz-Gómez G, Hawkins JC, Philipp J, Künze G, Wodtke R, Löser R, Fahmy K, Pisabarro MT. Ruiz-Gómez G, et al. PLoS One. 2016 Apr 28;11(4):e0154046. doi: 10.1371/journal.pone.0154046. eCollection 2016. PLoS One. 2016. PMID: 27123592 Free PMC article.

5

Sulfated hyaluronan improves bone regeneration of diabetic rats by binding sclerostin and enhancing osteoblast function.

Picke AK, Salbach-Hirsch J, Hintze V, Rother S, Rauner M, Kascholke C, Möller S, Bernhardt R, Rammelt S, Pisabarro MT, Ruiz-Gómez G, Schnabelrauch M, Schulz-Siegmund M, Hacker MC, Scharnweber D, Hofbauer C, Hofbauer LC. Picke AK, et al. Biomaterials. 2016 Jul;96:11-23. doi: 10.1016/j.biomaterials.2016.04.013. Epub 2016 Apr 21. Biomaterials. 2016. PMID: 27131598

6

Sulfated hyaluronan attenuates inflammatory signaling pathways in macrophages involving induction of antioxidants.

Jouy F, Lohmann N, Wandel E, Ruiz-Gómez G, Pisabarro MT, Beck-Sickinger AG, Schnabelrauch M, Möller S, Simon JC, Kalkhof S, von Bergen M, Franz S. Jouy F, et al. Proteomics. 2017 May;17(10):e1700082. doi: 10.1002/pmic.201700082. Proteomics. 2017. PMID: 28337837

7

Hyaluronan/collagen hydrogels containing sulfated hyaluronan improve wound healing by sustained release of heparin-binding EGF-like growth factor.

Thönes S, Rother S, Wippold T, Blaszkiewicz J, Balamurugan K, Moeller S, Ruiz-Gómez G, Schnabelrauch M, Scharnweber D, Saalbach A, Rademann J, Pisabarro MT, Hintze V, Anderegg U. Thönes S, et al. Acta Biomater. 2019 Mar 1;86:135-147. doi: 10.1016/j.actbio.2019.01.029. Epub 2019 Jan 17. Acta Biomater. 2019. PMID: 30660005

8

Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG-protein binding.

Köhling S, Blaszkiewicz J, Ruiz-Gómez G, Fernández-Bachiller MI, Lemmnitzer K, Panitz N, Beck-Sickinger AG, Schiller J, Pisabarro MT, Rademann J. Köhling S, et al. Chem Sci. 2018 Nov 1;10(3):866-878. doi: 10.1039/c8sc03649g. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774881 Free PMC article.

9

Glycosaminoglycans influence enzyme activity of MMP2 and MMP2/TIMP3 complex formation - Insights at cellular and molecular level.

Ruiz-Gómez G, Vogel S, Möller S, Pisabarro MT, Hempel U. Ruiz-Gómez G, et al. Sci Rep. 2019 Mar 20;9(1):4905. doi: 10.1038/s41598-019-41355-2. Sci Rep. 2019. PMID: 30894640 Free PMC article.

10

Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A.

Koehler L, Ruiz-Gómez G, Balamurugan K, Rother S, Freyse J, Möller S, Schnabelrauch M, Köhling S, Djordjevic S, Scharnweber D, Rademann J, Pisabarro MT, Hintze V. Koehler L, et al. Among authors: ruiz gomez g. Sci Rep. 2019 Dec 2;9(1):18143. doi: 10.1038/s41598-019-54211-0. Sci Rep. 2019. PMID: 31792253 Free PMC article.

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