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Nε-Acryloyllysine Piperazides as Irreversible Inhibitors of Transglutaminase 2: Synthesis, Structure-Activity Relationships, and Pharmacokinetic Profiling.
Wodtke R, Hauser C, Ruiz-Gómez G, Jäckel E, Bauer D, Lohse M, Wong A, Pufe J, Ludwig FA, Fischer S, Hauser S, Greif D, Pisabarro MT, Pietzsch J, Pietsch M, Löser R. Wodtke R, et al. Among authors: lohse m. J Med Chem. 2018 May 24;61(10):4528-4560. doi: 10.1021/acs.jmedchem.8b00286. Epub 2018 May 10. J Med Chem. 2018. PMID: 29664627
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Fasciani I, Petragnano F, Wang Z, Edwards R, Telugu N, Pietrantoni I, Zabel U, Zauber H, Grieben M, Terzenidou ME, Di Gregorio J, Pellegrini C, Santini S Jr, Taddei AR, Pohl B, Aringhieri S, Carli M, Aloisi G, Marampon F, Charlesworth E, Roman A, Diecke S, Flati V, Giorgi F, Amicarelli F, Tobin AB, Scarselli M, Tokatlidis K, Rossi M, Lohse MJ, Annibale P, Maggio R. Fasciani I, et al. Among authors: lohse mj. PLoS Biol. 2024 Apr 29;22(4):e3002582. doi: 10.1371/journal.pbio.3002582. eCollection 2024 Apr. PLoS Biol. 2024. PMID: 38683874 Free PMC article.
ADAM19 cleaves the PTH receptor and associates with brachydactyly type E.
Aydin A, Klenk C, Nemec K, Işbilir A, Martin LM, Zauber H, Rrustemi T, Toka HR, Schuster H, Gong M, Stricker S, Bock A, Bähring S, Selbach M, Lohse MJ, Luft FC. Aydin A, et al. Among authors: lohse mj. Life Sci Alliance. 2024 Feb 8;7(4):e202302400. doi: 10.26508/lsa.202302400. Print 2024 Apr. Life Sci Alliance. 2024. PMID: 38331475 Free PMC article.
456 results