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Smoke-induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in chronic obstructive pulmonary disease.
Kapchinsky S, Vuda M, Miguez K, Elkrief D, de Souza AR, Baglole CJ, Aare S, MacMillan NJ, Baril J, Rozakis P, Sonjak V, Pion C, Aubertin-Leheudre M, Morais JA, Jagoe RT, Bourbeau J, Taivassalo T, Hepple RT. Kapchinsky S, et al. Among authors: taivassalo t. J Physiol. 2018 Jul;596(14):2865-2881. doi: 10.1113/JP275558. Epub 2018 May 19. J Physiol. 2018. PMID: 29663403 Free PMC article.
Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle.
Konokhova Y, Spendiff S, Jagoe RT, Aare S, Kapchinsky S, MacMillan NJ, Rozakis P, Picard M, Aubertin-Leheudre M, Pion CH, Bourbeau J, Hepple RT, Taivassalo T. Konokhova Y, et al. Among authors: taivassalo t. Skelet Muscle. 2016 Feb 18;6:10. doi: 10.1186/s13395-016-0083-9. eCollection 2016. Skelet Muscle. 2016. PMID: 26893822 Free PMC article.
Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians.
Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT. Spendiff S, et al. Among authors: taivassalo t. J Physiol. 2016 Dec 15;594(24):7361-7379. doi: 10.1113/JP272487. Epub 2016 Oct 23. J Physiol. 2016. PMID: 27619626 Free PMC article.
Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease.
MacMillan NJ, Kapchinsky S, Konokhova Y, Gouspillou G, de Sousa Sena R, Jagoe RT, Baril J, Carver TE, Andersen RE, Richard R, Perrault H, Bourbeau J, Hepple RT, Taivassalo T. MacMillan NJ, et al. Among authors: taivassalo t. Front Physiol. 2017 Mar 3;8:114. doi: 10.3389/fphys.2017.00114. eCollection 2017. Front Physiol. 2017. PMID: 28316572 Free PMC article.
Chronic aryl hydrocarbon receptor activity phenocopies smoking-induced skeletal muscle impairment.
Thome T, Miguez K, Willms AJ, Burke SK, Chandran V, de Souza AR, Fitzgerald LF, Baglole C, Anagnostou ME, Bourbeau J, Jagoe RT, Morais JA, Goddard Y, Taivassalo T, Ryan TE, Hepple RT. Thome T, et al. Among authors: taivassalo t. J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):589-604. doi: 10.1002/jcsm.12826. Epub 2021 Nov 1. J Cachexia Sarcopenia Muscle. 2022. PMID: 34725955 Free PMC article.
Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans.
Gouspillou G, Sgarioto N, Kapchinsky S, Purves-Smith F, Norris B, Pion CH, Barbat-Artigas S, Lemieux F, Taivassalo T, Morais JA, Aubertin-Leheudre M, Hepple RT. Gouspillou G, et al. Among authors: taivassalo t. FASEB J. 2014 Apr;28(4):1621-33. doi: 10.1096/fj.13-242750. Epub 2013 Dec 26. FASEB J. 2014. PMID: 24371120
68 results