Kapanidis AN - Search Results

1

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria.

Dulin D, Bauer DLV, Malinen AM, Bakermans JJW, Kaller M, Morichaud Z, Petushkov I, Depken M, Brodolin K, Kulbachinskiy A, Kapanidis AN. Dulin D, et al. Among authors: kapanidis an. Nat Commun. 2018 Apr 16;9(1):1478. doi: 10.1038/s41467-018-03902-9. Nat Commun. 2018. PMID: 29662062 Free PMC article.

2

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism.

Kapanidis AN, Margeat E, Ho SO, Kortkhonjia E, Weiss S, Ebright RH. Kapanidis AN, et al. Science. 2006 Nov 17;314(5802):1144-7. doi: 10.1126/science.1131399. Science. 2006. PMID: 17110578 Free PMC article.

3

Single-molecule FRET analysis of protein-DNA complexes.

Heilemann M, Hwang LC, Lymperopoulos K, Kapanidis AN. Heilemann M, et al. Among authors: kapanidis an. Methods Mol Biol. 2009;543:503-21. doi: 10.1007/978-1-60327-015-1_29. Methods Mol Biol. 2009. PMID: 19378183

4

Monitoring multiple distances within a single molecule using switchable FRET.

Uphoff S, Holden SJ, Le Reste L, Periz J, van de Linde S, Heilemann M, Kapanidis AN. Uphoff S, et al. Among authors: kapanidis an. Nat Methods. 2010 Oct;7(10):831-6. doi: 10.1038/nmeth.1502. Epub 2010 Sep 5. Nat Methods. 2010. PMID: 20818380

5

Sensing DNA opening in transcription using quenchable Förster resonance energy transfer.

Cordes T, Santoso Y, Tomescu AI, Gryte K, Hwang LC, Camará B, Wigneshweraraj S, Kapanidis AN. Cordes T, et al. Among authors: kapanidis an. Biochemistry. 2010 Nov 2;49(43):9171-80. doi: 10.1021/bi101184g. Biochemistry. 2010. PMID: 20818825

6

The transcription bubble of the RNA polymerase-promoter open complex exhibits conformational heterogeneity and millisecond-scale dynamics: implications for transcription start-site selection.

Robb NC, Cordes T, Hwang LC, Gryte K, Duchi D, Craggs TD, Santoso Y, Weiss S, Ebright RH, Kapanidis AN. Robb NC, et al. Among authors: kapanidis an. J Mol Biol. 2013 Mar 11;425(5):875-85. doi: 10.1016/j.jmb.2012.12.015. Epub 2012 Dec 28. J Mol Biol. 2013. PMID: 23274143 Free PMC article.

7

Single-molecule DNA repair in live bacteria.

Uphoff S, Reyes-Lamothe R, Garza de Leon F, Sherratt DJ, Kapanidis AN. Uphoff S, et al. Among authors: kapanidis an. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8063-8. doi: 10.1073/pnas.1301804110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630273 Free PMC article.

8

Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion.

Hohlbein J, Aigrain L, Craggs TD, Bermek O, Potapova O, Shoolizadeh P, Grindley ND, Joyce CM, Kapanidis AN. Hohlbein J, et al. Among authors: kapanidis an. Nat Commun. 2013;4:2131. doi: 10.1038/ncomms3131. Nat Commun. 2013. PMID: 23831915 Free PMC article.

9

In vivo single-molecule imaging of bacterial DNA replication, transcription, and repair.

Stracy M, Uphoff S, Garza de Leon F, Kapanidis AN. Stracy M, et al. Among authors: kapanidis an. FEBS Lett. 2014 Oct 1;588(19):3585-94. doi: 10.1016/j.febslet.2014.05.026. Epub 2014 May 23. FEBS Lett. 2014. PMID: 24859634 Free article. Review.

10

Live-cell superresolution microscopy reveals the organization of RNA polymerase in the bacterial nucleoid.

Stracy M, Lesterlin C, Garza de Leon F, Uphoff S, Zawadzki P, Kapanidis AN. Stracy M, et al. Among authors: kapanidis an. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):E4390-9. doi: 10.1073/pnas.1507592112. Epub 2015 Jul 29. Proc Natl Acad Sci U S A. 2015. PMID: 26224838 Free PMC article.

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