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Lymphatic exosomes promote dendritic cell migration along guidance cues.
Brown M, Johnson LA, Leone DA, Majek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong YK, Bennett KL, Kain R, Detmar M, Sixt M, Jackson DG, Kerjaschki D. Brown M, et al. J Cell Biol. 2018 Jun 4;217(6):2205-2221. doi: 10.1083/jcb.201612051. Epub 2018 Apr 12. J Cell Biol. 2018. PMID: 29650776 Free PMC article.
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.
Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M. Leithner A, et al. Among authors: brown m. Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24. Nat Cell Biol. 2016. PMID: 27775702
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S. Martins R, et al. Among authors: brown m. Nat Immunol. 2016 Dec;17(12):1361-1372. doi: 10.1038/ni.3590. Epub 2016 Oct 31. Nat Immunol. 2016. PMID: 27798618
Multitier mechanics control stromal adaptations in the swelling lymph node.
Assen FP, Abe J, Hons M, Hauschild R, Shamipour S, Kaufmann WA, Costanzo T, Krens G, Brown M, Ludewig B, Hippenmeyer S, Heisenberg CP, Weninger W, Hannezo E, Luther SA, Stein JV, Sixt M. Assen FP, et al. Among authors: brown m. Nat Immunol. 2022 Aug;23(8):1246-1255. doi: 10.1038/s41590-022-01257-4. Epub 2022 Jul 11. Nat Immunol. 2022. PMID: 35817845 Free PMC article.
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