Pardo L - Search Results

1

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase.

Navarro G, Cordomí A, Casadó-Anguera V, Moreno E, Cai NS, Cortés A, Canela EI, Dessauer CW, Casadó V, Pardo L, Lluís C, Ferré S. Navarro G, et al. Among authors: pardo l. Nat Commun. 2018 Mar 28;9(1):1242. doi: 10.1038/s41467-018-03522-3. Nat Commun. 2018. PMID: 29593213 Free PMC article.

2

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.

Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK. Bokoch MP, et al. Among authors: pardo l. Nature. 2010 Jan 7;463(7277):108-12. doi: 10.1038/nature08650. Nature. 2010. PMID: 20054398 Free PMC article.

3

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers.

Navarro G, Ferré S, Cordomi A, Moreno E, Mallol J, Casadó V, Cortés A, Hoffmann H, Ortiz J, Canela EI, Lluís C, Pardo L, Franco R, Woods AS. Navarro G, et al. Among authors: pardo l. J Biol Chem. 2010 Aug 27;285(35):27346-27359. doi: 10.1074/jbc.M110.115634. Epub 2010 Jun 18. J Biol Chem. 2010. PMID: 20562103 Free PMC article.

4

The G-protein coupled receptor family: actors with many faces.

Liapakis G, Cordomí A, Pardo L. Liapakis G, et al. Among authors: pardo l. Curr Pharm Des. 2012;18(2):175-85. doi: 10.2174/138161212799040529. Curr Pharm Des. 2012. PMID: 22229577 Review.

5

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.

Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, Granier S. Manglik A, et al. Among authors: pardo l. Nature. 2012 Mar 21;485(7398):321-6. doi: 10.1038/nature10954. Nature. 2012. PMID: 22437502 Free PMC article.

6

A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.

Blättermann S, Peters L, Ottersbach PA, Bock A, Konya V, Weaver CD, Gonzalez A, Schröder R, Tyagi R, Luschnig P, Gäb J, Hennen S, Ulven T, Pardo L, Mohr K, Gütschow M, Heinemann A, Kostenis E. Blättermann S, et al. Among authors: pardo l. Nat Chem Biol. 2012 Jul;8(7):631-8. doi: 10.1038/nchembio.962. Epub 2012 May 27. Nat Chem Biol. 2012. PMID: 22634634

7

Impact of helix irregularities on sequence alignment and homology modeling of G protein-coupled receptors.

Gonzalez A, Cordomí A, Caltabiano G, Pardo L. Gonzalez A, et al. Among authors: pardo l. Chembiochem. 2012 Jul 9;13(10):1393-9. doi: 10.1002/cbic.201200189. Chembiochem. 2012. PMID: 22761034 Review.

8

The role of hydrophobic amino acids in the structure and function of the rhodopsin family of G protein-coupled receptors.

Caltabiano G, Gonzalez A, Cordomí A, Campillo M, Pardo L. Caltabiano G, et al. Among authors: pardo l. Methods Enzymol. 2013;520:99-115. doi: 10.1016/B978-0-12-391861-1.00005-8. Methods Enzymol. 2013. PMID: 23332697

9

Ligand binding determinants for angiotensin II type 1 receptor from computer simulations.

Matsoukas MT, Cordomí A, Ríos S, Pardo L, Tselios T. Matsoukas MT, et al. Among authors: pardo l. J Chem Inf Model. 2013 Nov 25;53(11):2874-83. doi: 10.1021/ci400400m. Epub 2013 Oct 25. J Chem Inf Model. 2013. PMID: 24090110

10

Modeling of G protein-coupled receptors using crystal structures: from monomers to signaling complexes.

Gonzalez A, Cordomí A, Matsoukas M, Zachmann J, Pardo L. Gonzalez A, et al. Among authors: pardo l. Adv Exp Med Biol. 2014;796:15-33. doi: 10.1007/978-94-007-7423-0_2. Adv Exp Med Biol. 2014. PMID: 24158799 Review.

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