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Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome.
Aoidi R, Houde N, Landry-Truchon K, Holter M, Jacquet K, Charron L, Krishnaswami SR, Yu BD, Rauen KA, Bisson N, Newbern J, Charron J. Aoidi R, et al. Among authors: newbern j. Dis Model Mech. 2018 Mar 13;11(3):dmm031278. doi: 10.1242/dmm.031278. Dis Model Mech. 2018. PMID: 29590634 Free PMC article.
Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development.
Newbern J, Zhong J, Wickramasinghe RS, Li X, Wu Y, Samuels I, Cherosky N, Karlo JC, O'Loughlin B, Wikenheiser J, Gargesha M, Doughman YQ, Charron J, Ginty DD, Watanabe M, Saitta SC, Snider WD, Landreth GE. Newbern J, et al. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17115-20. doi: 10.1073/pnas.0805239105. Epub 2008 Oct 24. Proc Natl Acad Sci U S A. 2008. PMID: 18952847 Free PMC article.
MEK Is a Key Regulator of Gliogenesis in the Developing Brain.
Li X, Newbern JM, Wu Y, Morgan-Smith M, Zhong J, Charron J, Snider WD. Li X, et al. Among authors: newbern jm. Neuron. 2012 Sep 20;75(6):1035-50. doi: 10.1016/j.neuron.2012.08.031. Neuron. 2012. PMID: 22998872 Free PMC article.
Hyperactive MEK1 Signaling in Cortical GABAergic Neurons Promotes Embryonic Parvalbumin Neuron Loss and Defects in Behavioral Inhibition.
Holter MC, Hewitt LT, Nishimura KJ, Knowles SJ, Bjorklund GR, Shah S, Fry NR, Rees KP, Gupta TA, Daniels CW, Li G, Marsh S, Treiman DM, Olive MF, Anderson TR, Sanabria F, Snider WD, Newbern JM. Holter MC, et al. Among authors: newbern jm. Cereb Cortex. 2021 May 10;31(6):3064-3081. doi: 10.1093/cercor/bhaa413. Cereb Cortex. 2021. PMID: 33570093 Free PMC article.
40 results