Proctor MA - Search Results

1

Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo.

Stevenson AJ, Ager EI, Proctor MA, Škalamera D, Heaton A, Brown D, Gabrielli BG. Stevenson AJ, et al. Among authors: proctor ma. Sci Rep. 2018 Mar 23;8(1):5144. doi: 10.1038/s41598-018-22882-w. Sci Rep. 2018. PMID: 29572477 Free PMC article.

2

Inhibition of Aurora A and Aurora B Is Required for the Sensitivity of HPV-Driven Cervical Cancers to Aurora Kinase Inhibitors.

Martin D, Fallaha S, Proctor M, Stevenson A, Perrin L, McMillan N, Gabrielli B. Martin D, et al. Mol Cancer Ther. 2017 Sep;16(9):1934-1941. doi: 10.1158/1535-7163.MCT-17-0159. Epub 2017 May 18. Mol Cancer Ther. 2017. PMID: 28522591

3

Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo.

Oo ZY, Stevenson AJ, Proctor M, Daignault SM, Walpole S, Lanagan C, Chen J, Škalamera D, Spoerri L, Ainger SA, Sturm RA, Haass NK, Gabrielli B. Oo ZY, et al. Clin Cancer Res. 2018 Jun 15;24(12):2901-2912. doi: 10.1158/1078-0432.CCR-17-2701. Epub 2018 Mar 13. Clin Cancer Res. 2018. PMID: 29535131

4

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine.

Oo ZY, Proctor M, Stevenson AJ, Nazareth D, Fernando M, Daignault SM, Lanagan C, Walpole S, Bonazzi V, Škalamera D, Snell C, Haass NK, Larsen JE, Gabrielli B. Oo ZY, et al. Mol Oncol. 2019 Jul;13(7):1503-1518. doi: 10.1002/1878-0261.12497. Epub 2019 Jun 14. Mol Oncol. 2019. PMID: 31044505 Free PMC article.

5

Dysregulated G2 phase checkpoint recovery pathway reduces DNA repair efficiency and increases chromosomal instability in a wide range of tumours.

Fernando M, Duijf PHG, Proctor M, Stevenson AJ, Ehmann A, Vora S, Skalamera D, Adams M, Gabrielli B. Fernando M, et al. Oncogenesis. 2021 May 15;10(5):41. doi: 10.1038/s41389-021-00329-8. Oncogenesis. 2021. PMID: 33993200 Free PMC article.

6

Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression.

Proctor M, Gonzalez Cruz JL, Daignault-Mill SM, Veitch M, Zeng B, Ehmann A, Sabdia M, Snell C, Keane C, Dolcetti R, Haass NK, Wells JW, Gabrielli B. Proctor M, et al. Cancers (Basel). 2021 Jul 25;13(15):3733. doi: 10.3390/cancers13153733. Cancers (Basel). 2021. PMID: 34359633 Free PMC article.

7

Checkpoint kinase 1 inhibitor + low-dose hydroxyurea efficiently kills BRAF inhibitor- and immune checkpoint inhibitor-resistant melanomas.

Zeng Z, Ngo HL, Proctor M, Rizos H, Dolcetti R, Cruz JG, Wells JW, Gabrielli B. Zeng Z, et al. Pigment Cell Melanoma Res. 2024 Jan;37(1):45-50. doi: 10.1111/pcmr.13120. Epub 2023 Aug 23. Pigment Cell Melanoma Res. 2024. PMID: 37614154

8

The ATM Ser49Cys Variant Effects ATM Function as a Regulator of Oncogene-Induced Senescence.

Atkinson C, McInerney-Leo AM, Proctor M, Lanagan C, Stevenson AJ, Dehkhoda F, Caole M, Maas E, Ainger S, Pritchard AL, Johansson PA, Leo P, Hayward NK, Sturm RA, Duncan EL, Gabrielli B. Atkinson C, et al. Int J Mol Sci. 2024 Jan 29;25(3):1664. doi: 10.3390/ijms25031664. Int J Mol Sci. 2024. PMID: 38338943 Free PMC article.

9

Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins.

Das I, Png CW, Oancea I, Hasnain SZ, Lourie R, Proctor M, Eri RD, Sheng Y, Crane DI, Florin TH, McGuckin MA. Das I, et al. Among authors: proctor m. J Exp Med. 2013 Jun 3;210(6):1201-16. doi: 10.1084/jem.20121268. Epub 2013 May 6. J Exp Med. 2013. PMID: 23650437 Free PMC article.

10

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism.

Oancea I, Movva R, Das I, Aguirre de Cárcer D, Schreiber V, Yang Y, Purdon A, Harrington B, Proctor M, Wang R, Sheng Y, Lobb M, Lourie R, Ó Cuív P, Duley JA, Begun J, Florin TH. Oancea I, et al. Gut. 2017 Jan;66(1):59-69. doi: 10.1136/gutjnl-2015-310874. Epub 2016 Jul 13. Gut. 2017. PMID: 27411368 Free PMC article.

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