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Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.
Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C. Chantôme A, et al. Among authors: jaffres pa. Cancer Res. 2013 Aug 1;73(15):4852-61. doi: 10.1158/0008-5472.CAN-12-4572. Epub 2013 Jun 17. Cancer Res. 2013. PMID: 23774210
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: jaffres pa. Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786. Oncotarget. 2016. PMID: 27102434 Free PMC article.
New Disaccharide-Based Ether Lipids as SK3 Ion Channel Inhibitors.
Berthe W, Sevrain CM, Chantôme A, Bouchet AM, Gueguinou M, Fourbon Y, Potier-Cartereau M, Haelters JP, Couthon-Gourvès H, Vandier C, Jaffrès PA. Berthe W, et al. Among authors: jaffres pa. ChemMedChem. 2016 Jul 19;11(14):1531-9. doi: 10.1002/cmdc.201600147. Epub 2016 Jun 9. ChemMedChem. 2016. PMID: 27278812
Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy.
Jaffrès PA, Gajate C, Bouchet AM, Couthon-Gourvès H, Chantôme A, Potier-Cartereau M, Besson P, Bougnoux P, Mollinedo F, Vandier C. Jaffrès PA, et al. Pharmacol Ther. 2016 Sep;165:114-31. doi: 10.1016/j.pharmthera.2016.06.003. Epub 2016 Jun 8. Pharmacol Ther. 2016. PMID: 27288726 Review.
Phosphonic acid: preparation and applications.
Sevrain CM, Berchel M, Couthon H, Jaffrès PA. Sevrain CM, et al. Among authors: jaffres pa. Beilstein J Org Chem. 2017 Oct 20;13:2186-2213. doi: 10.3762/bjoc.13.219. eCollection 2017. Beilstein J Org Chem. 2017. PMID: 29114326 Free PMC article. Review.
Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity.
Kouba S, Braire J, Félix R, Chantôme A, Jaffrès PA, Lebreton J, Dubreuil D, Pipelier M, Zhang X, Trebak M, Vandier C, Mathé-Allainmat M, Potier-Cartereau M. Kouba S, et al. Among authors: jaffres pa. Eur J Med Chem. 2020 Jan 15;186:111854. doi: 10.1016/j.ejmech.2019.111854. Epub 2019 Nov 9. Eur J Med Chem. 2020. PMID: 31753515
83 results