Wilkinson-White LE - Search Results

1

The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.

Wai DCC, Szyszka TN, Campbell AE, Kwong C, Wilkinson-White LE, Silva APG, Low JKK, Kwan AH, Gamsjaeger R, Chalmers JD, Patrick WM, Lu B, Vakoc CR, Blobel GA, Mackay JP. Wai DCC, et al. Among authors: wilkinson white le. J Biol Chem. 2018 May 11;293(19):7160-7175. doi: 10.1074/jbc.RA117.000678. Epub 2018 Mar 22. J Biol Chem. 2018. PMID: 29567837 Free PMC article.

2

1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex.

Wilkinson-White LE, Dastmalchi S, Kwan AH, Ryan DP, Mackay JP, Matthews JM. Wilkinson-White LE, et al. Biomol NMR Assign. 2010 Oct;4(2):203-6. doi: 10.1007/s12104-010-9240-y. Epub 2010 Jun 19. Biomol NMR Assign. 2010. PMID: 20563763

3

Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1.

Wilkinson-White L, Gamsjaeger R, Dastmalchi S, Wienert B, Stokes PH, Crossley M, Mackay JP, Matthews JM. Wilkinson-White L, et al. Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14443-8. doi: 10.1073/pnas.1105898108. Epub 2011 Aug 15. Proc Natl Acad Sci U S A. 2011. PMID: 21844373 Free PMC article.

4

Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex.

Dastmalchi S, Wilkinson-White L, Kwan AH, Gamsjaeger R, Mackay JP, Matthews JM. Dastmalchi S, et al. Protein Sci. 2012 Nov;21(11):1768-74. doi: 10.1002/pro.2153. Epub 2012 Sep 25. Protein Sci. 2012. PMID: 22936624 Free PMC article.

5

Analysis of disease-causing GATA1 mutations in murine gene complementation systems.

Campbell AE, Wilkinson-White L, Mackay JP, Matthews JM, Blobel GA. Campbell AE, et al. Blood. 2013 Jun 27;121(26):5218-27. doi: 10.1182/blood-2013-03-488080. Epub 2013 May 23. Blood. 2013. PMID: 23704091 Free PMC article.

6

Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.

Faoro C, Wilkinson-White L, Kwan AH, Ataide SF. Faoro C, et al. PLoS One. 2018 Jul 25;13(7):e0200387. doi: 10.1371/journal.pone.0200387. eCollection 2018. PLoS One. 2018. PMID: 30044812 Free PMC article.

7

Cyclic peptides can engage a single binding pocket through highly divergent modes.

Patel K, Walport LJ, Walshe JL, Solomon PD, Low JKK, Tran DH, Mouradian KS, Silva APG, Wilkinson-White L, Norman A, Franck C, Matthews JM, Guss JM, Payne RJ, Passioura T, Suga H, Mackay JP. Patel K, et al. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26728-26738. doi: 10.1073/pnas.2003086117. Epub 2020 Oct 12. Proc Natl Acad Sci U S A. 2020. PMID: 33046654 Free PMC article.

8

Contrasting DNA-binding behaviour by ISL1 and LHX3 underpins differential gene targeting in neuronal cell specification.

Smith NC, Wilkinson-White LE, Kwan AHY, Trewhella J, Matthews JM. Smith NC, et al. Among authors: wilkinson white le. J Struct Biol X. 2020 Dec 15;5:100043. doi: 10.1016/j.yjsbx.2020.100043. eCollection 2021. J Struct Biol X. 2020. PMID: 33458649 Free PMC article.

9

BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism.

Patel K, Solomon PD, Walshe JL, Ford DJ, Wilkinson-White L, Payne RJ, Low JKK, Mackay JP. Patel K, et al. Biochemistry. 2021 Mar 9;60(9):648-662. doi: 10.1021/acs.biochem.0c00816. Epub 2021 Feb 23. Biochemistry. 2021. PMID: 33620209

10

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain.

Adams LA, Wilkinson-White LE, Gunzburg MJ, Headey SJ, Mohanty B, Scanlon MJ, Capuano B, Mackay JP, Doak BC. Adams LA, et al. Among authors: wilkinson white le. J Med Chem. 2023 Apr 27;66(8):5859-5872. doi: 10.1021/acs.jmedchem.3c00137. Epub 2023 Apr 18. J Med Chem. 2023. PMID: 37071570

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