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The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.
Wai DCC, Szyszka TN, Campbell AE, Kwong C, Wilkinson-White LE, Silva APG, Low JKK, Kwan AH, Gamsjaeger R, Chalmers JD, Patrick WM, Lu B, Vakoc CR, Blobel GA, Mackay JP. Wai DCC, et al. J Biol Chem. 2018 May 11;293(19):7160-7175. doi: 10.1074/jbc.RA117.000678. Epub 2018 Mar 22. J Biol Chem. 2018. PMID: 29567837 Free PMC article.
Conformational exchange in the potassium channel blocker ShK.
Iwakawa N, Baxter NJ, Wai DCC, Fowler NJ, Morales RAV, Sugase K, Norton RS, Williamson MP. Iwakawa N, et al. Among authors: wai dcc. Sci Rep. 2019 Dec 17;9(1):19307. doi: 10.1038/s41598-019-55806-3. Sci Rep. 2019. PMID: 31848433 Free PMC article.
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