Matinkhoo K - Search Results

1

Synthesis of the Death-Cap Mushroom Toxin α-Amanitin.

Matinkhoo K, Pryyma A, Todorovic M, Patrick BO, Perrin DM. Matinkhoo K, et al. J Am Chem Soc. 2018 May 30;140(21):6513-6517. doi: 10.1021/jacs.7b12698. Epub 2018 Mar 21. J Am Chem Soc. 2018. PMID: 29561592

2

Synthesis of a Cytotoxic Amanitin for Biorthogonal Conjugation.

Zhao L, May JP, Blanc A, Dietrich DJ, Loonchanta A, Matinkhoo K, Pryyma A, Perrin DM. Zhao L, et al. Among authors: matinkhoo k. Chembiochem. 2015 Jul 6;16(10):1420-5. doi: 10.1002/cbic.201500226. Epub 2015 Jun 3. Chembiochem. 2015. PMID: 26043184

3

Design, Synthesis, and Biochemical Evaluation of Alpha-Amanitin Derivatives Containing Analogs of the trans-Hydroxyproline Residue for Potential Use in Antibody-Drug Conjugates.

Matinkhoo K, Wong AAWL, Hambira CM, Kato B, Wei C, Müller C, Hechler T, Braun A, Gallo F, Pahl A, Perrin DM. Matinkhoo K, et al. Chemistry. 2021 Jul 16;27(40):10282-10292. doi: 10.1002/chem.202101373. Epub 2021 Jun 18. Chemistry. 2021. PMID: 34058032

4

Meeting key synthetic challenges in amanitin synthesis with a new cytotoxic analog: 5'-hydroxy-6'-deoxy-amanitin.

Pryyma A, Matinkhoo K, Wong AAWL, Perrin DM. Pryyma A, et al. Among authors: matinkhoo k. Chem Sci. 2020 Oct 15;11(43):11927-11935. doi: 10.1039/d0sc04150e. Chem Sci. 2020. PMID: 34094418 Free PMC article.

5

Scaling Amatoxin Synthesis with an Improved Route to (2S,3R,4R)-Dihydroxyisoleucine Exemplified by a Toxic, Clickable α-Amanitin Analogue.

Hambira CM, Matinkhoo K, Pryyma A, Patrick BO, Perrin DM. Hambira CM, et al. Among authors: matinkhoo k. J Org Chem. 2021 Apr 2;86(7):5362-5370. doi: 10.1021/acs.joc.0c03022. Epub 2021 Mar 12. J Org Chem. 2021. PMID: 33710901

6

Synthesis and evaluation of "Ama-Flash", a photocaged amatoxin prodrug for light-activated RNA Pol II inhibition and cell death.

Matinkhoo K, Pryyma A, Wong AAWL, Perrin DM. Matinkhoo K, et al. Chem Commun (Camb). 2021 Sep 21;57(75):9558-9561. doi: 10.1039/d1cc03279h. Chem Commun (Camb). 2021. PMID: 34477193

7

Synthesis and preliminary evaluation of octreotate conjugates of bioactive synthetic amatoxins for targeting somatostatin receptor (sstr2) expressing cells.

Pryyma A, Matinkhoo K, Bu YJ, Merkens H, Zhang Z, Bénard F, Perrin DM. Pryyma A, et al. Among authors: matinkhoo k. RSC Chem Biol. 2021 Oct 7;3(1):69-78. doi: 10.1039/d1cb00036e. eCollection 2022 Jan 5. RSC Chem Biol. 2021. PMID: 35128410 Free PMC article.

8

Novel Psilocin Prodrugs with Altered Pharmacological Properties as Candidate Therapies for Treatment-Resistant Anxiety Disorders.

Raithatha SA, Hagel JM, Matinkhoo K, Yu L, Press D, Cook SG, Sharma G, Dhananjaya D, Jensen G, Lee JB, Cai C, Gallant J, Bains J, Tucker JE, Facchini PJ. Raithatha SA, et al. Among authors: matinkhoo k. J Med Chem. 2024 Jan 25;67(2):1024-1043. doi: 10.1021/acs.jmedchem.3c01225. Epub 2023 Nov 20. J Med Chem. 2024. PMID: 37983270 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

8 results

Search Page