Sachsenmeier KF - Search Results

1

CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells.

Lupia M, Angiolini F, Bertalot G, Freddi S, Sachsenmeier KF, Chisci E, Kutryb-Zajac B, Confalonieri S, Smolenski RT, Giovannoni R, Colombo N, Bianchi F, Cavallaro U. Lupia M, et al. Among authors: sachsenmeier kf. Stem Cell Reports. 2018 Apr 10;10(4):1412-1425. doi: 10.1016/j.stemcr.2018.02.009. Epub 2018 Mar 15. Stem Cell Reports. 2018. PMID: 29551673 Free PMC article.

2

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action.

Geoghegan JC, Diedrich G, Lu X, Rosenthal K, Sachsenmeier KF, Wu H, Dall'Acqua WF, Damschroder MM. Geoghegan JC, et al. Among authors: sachsenmeier kf. MAbs. 2016;8(3):454-67. doi: 10.1080/19420862.2016.1143182. Epub 2016 Feb 8. MAbs. 2016. PMID: 26854859 Free PMC article.

3

Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses.

Young A, Ngiow SF, Barkauskas DS, Sult E, Hay C, Blake SJ, Huang Q, Liu J, Takeda K, Teng MWL, Sachsenmeier K, Smyth MJ. Young A, et al. Cancer Cell. 2016 Sep 12;30(3):391-403. doi: 10.1016/j.ccell.2016.06.025. Cancer Cell. 2016. PMID: 27622332 Free article.

4

Switching off CD73: a way to boost the activity of conventional and targeted antineoplastic therapies.

Antonioli L, Novitskiy SV, Sachsenmeier KF, Fornai M, Blandizzi C, Haskó G. Antonioli L, et al. Among authors: sachsenmeier kf. Drug Discov Today. 2017 Nov;22(11):1686-1696. doi: 10.1016/j.drudis.2017.06.005. Epub 2017 Jul 1. Drug Discov Today. 2017. PMID: 28676406 Review.

5

Development of a novel ectonucleotidase assay suitable for high-throughput screening.

Sachsenmeier KF, Hay C, Brand E, Clarke L, Rosenthal K, Guillard S, Rust S, Minter R, Hollingsworth R. Sachsenmeier KF, et al. J Biomol Screen. 2012 Aug;17(7):993-8. doi: 10.1177/1087057112443987. Epub 2012 Apr 20. J Biomol Screen. 2012. PMID: 22522649

6

Targeting CD73 in the tumor microenvironment with MEDI9447.

Hay CM, Sult E, Huang Q, Mulgrew K, Fuhrmann SR, McGlinchey KA, Hammond SA, Rothstein R, Rios-Doria J, Poon E, Holoweckyj N, Durham NM, Leow CC, Diedrich G, Damschroder M, Herbst R, Hollingsworth RE, Sachsenmeier KF. Hay CM, et al. Among authors: sachsenmeier kf. Oncoimmunology. 2016 Jul 11;5(8):e1208875. doi: 10.1080/2162402X.2016.1208875. eCollection 2016 Aug. Oncoimmunology. 2016. PMID: 27622077 Free PMC article.

7

Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases.

Vijayan D, Barkauskas DS, Stannard K, Sult E, Buonpane R, Takeda K, Teng MWL, Sachsenmeier K, Hay C, Smyth MJ. Vijayan D, et al. Oncoimmunology. 2017 Apr 5;6(5):e1312044. doi: 10.1080/2162402X.2017.1312044. eCollection 2017. Oncoimmunology. 2017. PMID: 28638737 Free PMC article.

8

Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence.

Mazor Y, Sachsenmeier KF, Yang C, Hansen A, Filderman J, Mulgrew K, Wu H, Dall'Acqua WF. Mazor Y, et al. Among authors: sachsenmeier kf. Sci Rep. 2017 Jan 9;7:40098. doi: 10.1038/srep40098. Sci Rep. 2017. PMID: 28067257 Free PMC article.

9

Improving target cell specificity using a novel monovalent bispecific IgG design.

Mazor Y, Oganesyan V, Yang C, Hansen A, Wang J, Liu H, Sachsenmeier K, Carlson M, Gadre DV, Borrok MJ, Yu XQ, Dall'Acqua W, Wu H, Chowdhury PS. Mazor Y, et al. MAbs. 2015;7(2):377-89. doi: 10.1080/19420862.2015.1007816. MAbs. 2015. PMID: 25621507 Free PMC article.

10

The application of mathematical modelling to the design of bispecific monoclonal antibodies.

van Steeg TJ, Bergmann KR, Dimasi N, Sachsenmeier KF, Agoram B. van Steeg TJ, et al. Among authors: sachsenmeier kf. MAbs. 2016;8(3):585-92. doi: 10.1080/19420862.2016.1141160. Epub 2016 Feb 24. MAbs. 2016. PMID: 26910134 Free PMC article.

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