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New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors.
Salerno S, García-Argáez AN, Barresi E, Taliani S, Simorini F, La Motta C, Amendola G, Tomassi S, Cosconati S, Novellino E, Da Settimo F, Marini AM, Via LD. Salerno S, et al. Among authors: simorini f. Eur J Med Chem. 2018 Apr 25;150:446-456. doi: 10.1016/j.ejmech.2018.03.013. Epub 2018 Mar 7. Eur J Med Chem. 2018. PMID: 29547832
Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.
Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: simorini f. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836
New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation.
Taliani S, Simorini F, Sergianni V, La Motta C, Da Settimo F, Cosimelli B, Abignente E, Greco G, Novellino E, Rossi L, Gremigni V, Spinetti F, Chelli B, Martini C. Taliani S, et al. Among authors: simorini f. J Med Chem. 2007 Jan 25;50(2):404-7. doi: 10.1021/jm061137o. J Med Chem. 2007. PMID: 17228885
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.
Primofiore G, Taliani S, Da Settimo F, Marini AM, La Motta C, Simorini F, Patrizi MP, Sergianni V, Novellino E, Greco G, Cosimelli B, Calderone V, Montali M, Besnard F, Martini C. Primofiore G, et al. Among authors: simorini f. J Med Chem. 2007 Apr 5;50(7):1627-34. doi: 10.1021/jm0607707. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335185
46 results