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Stimulating p53 down-under: a report from the 1st Australian p53 Workshop.
Neilsen PM, Braithwaite AW, Gamell C, Haupt S, Janic A, Strasser A, Wolyniec K, Haupt Y. Neilsen PM, et al. Among authors: haupt s, haupt y. Cell Death Differ. 2013 Dec;20(12):1753-6. doi: 10.1038/cdd.2013.2. Epub 2013 Feb 1. Cell Death Differ. 2013. PMID: 23370272 Free PMC article. No abstract available.
PML tumour suppression and beyond: therapeutic implications.
Gamell C, Jan Paul P, Haupt Y, Haupt S. Gamell C, et al. Among authors: haupt s, haupt y. FEBS Lett. 2014 Aug 19;588(16):2653-62. doi: 10.1016/j.febslet.2014.02.007. Epub 2014 Feb 15. FEBS Lett. 2014. PMID: 24548562 Free article. Review.
Targeting Mdmx to treat breast cancers with wild-type p53.
Haupt S, Buckley D, Pang JM, Panimaya J, Paul PJ, Gamell C, Takano EA, Lee YY, Hiddingh S, Rogers TM, Teunisse AF, Herold MJ, Marine JC, Fox SB, Jochemsen A, Haupt Y. Haupt S, et al. Among authors: haupt y. Cell Death Dis. 2015 Jul 16;6(7):e1821. doi: 10.1038/cddis.2015.173. Cell Death Dis. 2015. PMID: 26181202 Free PMC article.
The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.
Mansour M, Haupt S, Chan AL, Godde N, Rizzitelli A, Loi S, Caramia F, Deb S, Takano EA, Bishton M, Johnstone C, Monahan B, Levav-Cohen Y, Jiang YH, Yap AS, Fox S, Bernard O, Anderson R, Haupt Y. Mansour M, et al. Among authors: haupt s, haupt y. Cancer Res. 2016 Jul 15;76(14):4236-48. doi: 10.1158/0008-5472.CAN-15-1553. Epub 2016 May 26. Cancer Res. 2016. PMID: 27231202 Retracted.
Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP.
Paul PJ, Raghu D, Chan AL, Gulati T, Lambeth L, Takano E, Herold MJ, Hagekyriakou J, Vessella RL, Fedele C, Shackleton M, Williams ED, Fox S, Williams S, Haupt S, Gamell C, Haupt Y. Paul PJ, et al. Among authors: haupt s, haupt y. Oncogene. 2016 Dec 1;35(48):6235-6245. doi: 10.1038/onc.2016.159. Epub 2016 Sep 19. Oncogene. 2016. PMID: 27641331
Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer.
Gamell C, Gulati T, Levav-Cohen Y, Young RJ, Do H, Pilling P, Takano E, Watkins N, Fox SB, Russell P, Ginsberg D, Monahan BJ, Wright G, Dobrovic A, Haupt S, Solomon B, Haupt Y. Gamell C, et al. Among authors: haupt s, haupt y. Sci Signal. 2017 Jan 10;10(461):eaaf8223. doi: 10.1126/scisignal.aaf8223. Sci Signal. 2017. PMID: 28074012
MDM4 is a rational target for treating breast cancers with mutant p53.
Miranda PJ, Buckley D, Raghu D, Pang JB, Takano EA, Vijayakumaran R, Teunisse AF, Posner A, Procter T, Herold MJ, Gamell C, Marine JC, Fox SB, Jochemsen A, Haupt S, Haupt Y. Miranda PJ, et al. Among authors: haupt s, haupt y. J Pathol. 2017 Apr;241(5):661-670. doi: 10.1002/path.4877. Epub 2017 Mar 1. J Pathol. 2017. PMID: 28097652
E6AP promotes prostate cancer by reducing p27 expression.
Raghu D, Paul PJ, Gulati T, Deb S, Khoo C, Russo A, Gallo E, Blandino G, Chan AL, Takano E, Sandhu SK, Fox SB, Williams S, Haupt S, Gamell C, Haupt Y. Raghu D, et al. Among authors: haupt s, haupt y. Oncotarget. 2017 Jun 27;8(26):42939-42948. doi: 10.18632/oncotarget.17224. Oncotarget. 2017. PMID: 28477016 Free PMC article.
128 results