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Benchmark dose (BMD) modeling: current practice, issues, and challenges.
Haber LT, Dourson ML, Allen BC, Hertzberg RC, Parker A, Vincent MJ, Maier A, Boobis AR. Haber LT, et al. Among authors: boobis ar. Crit Rev Toxicol. 2018 May;48(5):387-415. doi: 10.1080/10408444.2018.1430121. Epub 2018 Mar 8. Crit Rev Toxicol. 2018. PMID: 29516780 Review.
A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens.
Felter SP, Conolly RB, Bercu JP, Bolger PM, Boobis AR, Bos PM, Carthew P, Doerrer NG, Goodman JI, Harrouk WA, Kirkland DJ, Lau SS, Llewellyn GC, Preston RJ, Schoeny R, Schnatter AR, Tritscher A, van Velsen F, Williams GM. Felter SP, et al. Among authors: boobis ar. Crit Rev Toxicol. 2011 Jul;41(6):507-44. doi: 10.3109/10408444.2011.552063. Epub 2011 May 18. Crit Rev Toxicol. 2011. PMID: 21591905 Review.
Selection of appropriate tumour data sets for Benchmark Dose Modelling (BMD) and derivation of a Margin of Exposure (MoE) for substances that are genotoxic and carcinogenic: considerations of biological relevance of tumour type, data quality and uncertainty assessment.
Edler L, Hart A, Greaves P, Carthew P, Coulet M, Boobis A, Williams GM, Smith B. Edler L, et al. Food Chem Toxicol. 2014 Aug;70:264-89. doi: 10.1016/j.fct.2013.10.030. Epub 2013 Oct 29. Food Chem Toxicol. 2014. PMID: 24176677 Free article.
The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.
Simon TW, Simons SS Jr, Preston RJ, Boobis AR, Cohen SM, Doerrer NG, Fenner-Crisp PA, McMullin TS, McQueen CA, Rowlands JC; RISK21 Dose-Response Subteam. Simon TW, et al. Among authors: boobis ar. Crit Rev Toxicol. 2014 Aug;44 Suppl 3:17-43. doi: 10.3109/10408444.2014.931925. Crit Rev Toxicol. 2014. PMID: 25070415 Review.
A framework for cumulative risk assessment in the 21st century.
Moretto A, Bachman A, Boobis A, Solomon KR, Pastoor TP, Wilks MF, Embry MR. Moretto A, et al. Crit Rev Toxicol. 2017 Feb;47(2):85-97. doi: 10.1080/10408444.2016.1211618. Epub 2016 Aug 11. Crit Rev Toxicol. 2017. PMID: 27685779 Free article. Review.
354 results