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Calnexin is necessary for T cell transmigration into the central nervous system.
Jung J, Eggleton P, Robinson A, Wang J, Gutowski N, Holley J, Newcombe J, Dudek E, Paul AM, Zochodne D, Kraus A, Power C, Agellon LB, Michalak M. Jung J, et al. Among authors: kraus a. JCI Insight. 2018 Mar 8;3(5):e98410. doi: 10.1172/jci.insight.98410. JCI Insight. 2018. PMID: 29515033 Free PMC article.
Calnexin deficiency leads to dysmyelination.
Kraus A, Groenendyk J, Bedard K, Baldwin TA, Krause KH, Dubois-Dauphin M, Dyck J, Rosenbaum EE, Korngut L, Colley NJ, Gosgnach S, Zochodne D, Todd K, Agellon LB, Michalak M. Kraus A, et al. J Biol Chem. 2010 Jun 11;285(24):18928-38. doi: 10.1074/jbc.M110.107201. Epub 2010 Apr 16. J Biol Chem. 2010. PMID: 20400506 Free PMC article.
Antisense oligonucleotides extend survival of prion-infected mice.
Raymond GJ, Zhao HT, Race B, Raymond LD, Williams K, Swayze EE, Graffam S, Le J, Caron T, Stathopoulos J, O'Keefe R, Lubke LL, Reidenbach AG, Kraus A, Schreiber SL, Mazur C, Cabin DE, Carroll JB, Minikel EV, Kordasiewicz H, Caughey B, Vallabh SM. Raymond GJ, et al. Among authors: kraus a. JCI Insight. 2019 Jul 30;5(16):e131175. doi: 10.1172/jci.insight.131175. JCI Insight. 2019. PMID: 31361599 Free PMC article.
671 results