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Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation.
Br J Pharmacol. 2018 May;175(10):1744-1759. doi: 10.1111/bph.14188. Epub 2018 Apr 6.
Br J Pharmacol. 2018.
PMID: 29498036
Free PMC article.
Natural and synthetic flavonoid modulation of TRPC5 channels.
Naylor J, Minard A, Gaunt HJ, Amer MS, Wilson LA, Migliore M, Cheung SY, Rubaiy HN, Blythe NM, Musialowski KE, Ludlow MJ, Evans WD, Green BL, Yang H, You Y, Li J, Fishwick CW, Muraki K, Beech DJ, Bon RS.
Naylor J, et al. Among authors: blythe nm.
Br J Pharmacol. 2016 Feb;173(3):562-74. doi: 10.1111/bph.13387. Epub 2016 Jan 13.
Br J Pharmacol. 2016.
PMID: 26565375
Free PMC article.
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(-)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase.
Ludlow MJ, Gaunt HJ, Rubaiy HN, Musialowski KE, Blythe NM, Vasudev NS, Muraki K, Beech DJ.
Ludlow MJ, et al. Among authors: blythe nm.
J Biol Chem. 2017 Jan 13;292(2):723-731. doi: 10.1074/jbc.M116.755678. Epub 2016 Nov 14.
J Biol Chem. 2017.
PMID: 27875305
Free PMC article.
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Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
Rubaiy HN, Ludlow MJ, Henrot M, Gaunt HJ, Miteva K, Cheung SY, Tanahashi Y, Hamzah N, Musialowski KE, Blythe NM, Appleby HL, Bailey MA, McKeown L, Taylor R, Foster R, Waldmann H, Nussbaumer P, Christmann M, Bon RS, Muraki K, Beech DJ.
Rubaiy HN, et al. Among authors: blythe nm.
J Biol Chem. 2017 May 19;292(20):8158-8173. doi: 10.1074/jbc.M116.773556. Epub 2017 Mar 21.
J Biol Chem. 2017.
PMID: 28325835
Free PMC article.
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Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion.
Blythe NM, Muraki K, Ludlow MJ, Stylianidis V, Gilbert HTJ, Evans EL, Cuthbertson K, Foster R, Swift J, Li J, Drinkhill MJ, van Nieuwenhoven FA, Porter KE, Beech DJ, Turner NA.
Blythe NM, et al.
J Biol Chem. 2019 Nov 15;294(46):17395-17408. doi: 10.1074/jbc.RA119.009167. Epub 2019 Oct 4.
J Biol Chem. 2019.
PMID: 31586031
Free PMC article.
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Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice.
Bartoli F, Evans EL, Blythe NM, Stewart L, Chuntharpursat-Bon E, Debant M, Musialowski KE, Lichtenstein L, Parsonage G, Futers TS, Turner NA, Beech DJ.
Bartoli F, et al. Among authors: blythe nm.
Cells. 2022 Apr 2;11(7):1199. doi: 10.3390/cells11071199.
Cells. 2022.
PMID: 35406763
Free PMC article.
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Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling.
Turner NA, Blythe NM.
Turner NA, et al. Among authors: blythe nm.
J Cardiovasc Dev Dis. 2019 Aug 7;6(3):27. doi: 10.3390/jcdd6030027.
J Cardiovasc Dev Dis. 2019.
PMID: 31394846
Free PMC article.
Review.
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