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Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach.
Tkaczyk C, Kasturirangan S, Minola A, Jones-Nelson O, Gunter V, Shi YY, Rosenthal K, Aleti V, Semenova E, Warrener P, Tabor D, Stover CK, Corti D, Rainey G, Sellman BR. Tkaczyk C, et al. Among authors: jones nelson o. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00629-17. doi: 10.1128/AAC.00629-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28584141 Free PMC article.
Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a Staphylococcus aureus dermonecrosis model.
Hilliard JJ, Datta V, Tkaczyk C, Hamilton M, Sadowska A, Jones-Nelson O, O'Day T, Weiss WJ, Szarka S, Nguyen V, Prokai L, Suzich J, Stover CK, Sellman BR. Hilliard JJ, et al. Among authors: jones nelson o. Antimicrob Agents Chemother. 2015 Jan;59(1):299-309. doi: 10.1128/AAC.03918-14. Epub 2014 Oct 27. Antimicrob Agents Chemother. 2015. PMID: 25348518 Free PMC article.
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections.
Cohen TS, Hilliard JJ, Jones-Nelson O, Keller AE, O'Day T, Tkaczyk C, DiGiandomenico A, Hamilton M, Pelletier M, Wang Q, Diep BA, Le VT, Cheng L, Suzich J, Stover CK, Sellman BR. Cohen TS, et al. Among authors: jones nelson o. Sci Transl Med. 2016 Mar 9;8(329):329ra31. doi: 10.1126/scitranslmed.aad9922. Sci Transl Med. 2016. PMID: 26962155
Staphylococcus aureus drives expansion of low-density neutrophils in diabetic mice.
Cohen TS, Takahashi V, Bonnell J, Tovchigrechko A, Chaerkady R, Yu W, Jones-Nelson O, Lee Y, Raja R, Hess S, Stover CK, Worthington JJ, Travis MA, Sellman BR. Cohen TS, et al. Among authors: jones nelson o. J Clin Invest. 2019 Apr 15;129(5):2133-2144. doi: 10.1172/JCI126938. eCollection 2019 Apr 15. J Clin Invest. 2019. PMID: 30985291 Free PMC article.
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Jones-Nelson O, Tovchigrechko A, Glover MS, Fernandes F, Rangaswamy U, Liu H, Tabor DE, Boyd J, Warrener P, Martinez J, Hilliard JJ, Stover CK, Yu W, DAngelo G, Hess S, Cohen TS, Sellman BR. Jones-Nelson O, et al. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02347-19. doi: 10.1128/AAC.02347-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32152087 Free PMC article.