Vaara M - Search Results

1

New polymyxin derivatives that display improved efficacy in animal infection models as compared to polymyxin B and colistin.

Vaara M. Vaara M. Med Res Rev. 2018 Sep;38(5):1661-1673. doi: 10.1002/med.21494. Epub 2018 Feb 27. Med Res Rev. 2018. PMID: 29485690 Review.

2

Polymyxin derivatives NAB739 and NAB815 are more effective than polymyxin B in murine Escherichia coli pyelonephritis.

Vaara M, Vaara T, Vingsbo Lundberg C. Vaara M, et al. Among authors: vaara t. J Antimicrob Chemother. 2018 Feb 1;73(2):452-455. doi: 10.1093/jac/dkx394. J Antimicrob Chemother. 2018. PMID: 29149329

3

Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics.

Vaara M. Vaara M. Molecules. 2019 Jan 11;24(2):249. doi: 10.3390/molecules24020249. Molecules. 2019. PMID: 30641878 Free PMC article. Review.

4

Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity.

Weber EJ, Lidberg KA, Wang L, Bammler TK, MacDonald JW, Li MJ, Redhair M, Atkins WM, Tran C, Hines KM, Herron J, Xu L, Monteiro MB, Ramm S, Vaidya V, Vaara M, Vaara T, Himmelfarb J, Kelly EJ. Weber EJ, et al. Among authors: vaara m. JCI Insight. 2018 Dec 20;3(24):e123673. doi: 10.1172/jci.insight.123673. JCI Insight. 2018. PMID: 30568031 Free PMC article.

5

Structure-activity studies on polymyxin derivatives carrying three positive charges only reveal a new class of compounds with strong antibacterial activity.

Vaara M, Vaara T, Tyrrell JM. Vaara M, et al. Among authors: vaara t. Peptides. 2017 May;91:8-12. doi: 10.1016/j.peptides.2017.03.002. Epub 2017 Mar 11. Peptides. 2017. PMID: 28300674

6

Polymyxins and their novel derivatives.

Vaara M. Vaara M. Curr Opin Microbiol. 2010 Oct;13(5):574-81. doi: 10.1016/j.mib.2010.09.002. Epub 2010 Sep 24. Curr Opin Microbiol. 2010. PMID: 20869908 Review.

7

The polymyxin derivative NAB739 is synergistic with several antibiotics against polymyxin-resistant strains of Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii.

Tyrrell JM, Aboklaish AF, Walsh TR, Vaara T, Vaara M. Tyrrell JM, et al. Among authors: vaara m. Peptides. 2019 Feb;112:149-153. doi: 10.1016/j.peptides.2018.12.006. Epub 2018 Dec 23. Peptides. 2019. PMID: 30586602

8

Novel derivatives of polymyxins.

Vaara M. Vaara M. J Antimicrob Chemother. 2013 Jun;68(6):1213-9. doi: 10.1093/jac/dkt039. Epub 2013 Feb 13. J Antimicrob Chemother. 2013. PMID: 23412346 Review.

9

Structure-activity studies on novel polymyxin derivatives that carry only three positive charges.

Vaara M, Vaara T. Vaara M, et al. Among authors: vaara t. Peptides. 2010 Dec;31(12):2318-21. doi: 10.1016/j.peptides.2010.09.010. Epub 2010 Sep 22. Peptides. 2010. PMID: 20868714

10

Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents.

Vaara M, Fox J, Loidl G, Siikanen O, Apajalahti J, Hansen F, Frimodt-Møller N, Nagai J, Takano M, Vaara T. Vaara M, et al. Among authors: vaara t. Antimicrob Agents Chemother. 2008 Sep;52(9):3229-36. doi: 10.1128/AAC.00405-08. Epub 2008 Jun 30. Antimicrob Agents Chemother. 2008. PMID: 18591267 Free PMC article.

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