Singaraja RR - Search Results

1

Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice.

Chevre R, Trigueros-Motos L, Castaño D, Chua T, Corlianò M, Patankar JV, Sng L, Sim L, Juin TL, Carissimo G, Ng LFP, Yi CNJ, Eliathamby CC, Groen AK, Hayden MR, Singaraja RR. Chevre R, et al. Among authors: singaraja rr. FASEB J. 2018 Jul;32(7):3792-3802. doi: 10.1096/fj.201701084RR. Epub 2018 Feb 26. FASEB J. 2018. PMID: 29481310

2

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates.

Martindale D, Hackam A, Wieczorek A, Ellerby L, Wellington C, McCutcheon K, Singaraja R, Kazemi-Esfarjani P, Devon R, Kim SU, Bredesen DE, Tufaro F, Hayden MR. Martindale D, et al. Nat Genet. 1998 Feb;18(2):150-4. doi: 10.1038/ng0298-150. Nat Genet. 1998. PMID: 9462744

3

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

Hackam AS, Singaraja R, Wellington CL, Metzler M, McCutcheon K, Zhang T, Kalchman M, Hayden MR. Hackam AS, et al. J Cell Biol. 1998 Jun 1;141(5):1097-105. doi: 10.1083/jcb.141.5.1097. J Cell Biol. 1998. PMID: 9606203 Free PMC article.

4

In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease.

Hackam AS, Singaraja R, Zhang T, Gan L, Hayden MR. Hackam AS, et al. Hum Mol Genet. 1999 Jan;8(1):25-33. doi: 10.1093/hmg/8.1.25. Hum Mol Genet. 1999. PMID: 9887328

5

Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.

Hackam AS, Hodgson JG, Singaraja R, Zhang T, Gan L, Gutekunst CA, Hersch SM, Hayden MR. Hackam AS, et al. Philos Trans R Soc Lond B Biol Sci. 1999 Jun 29;354(1386):1047-55. doi: 10.1098/rstb.1999.0457. Philos Trans R Soc Lond B Biol Sci. 1999. PMID: 10434304 Free PMC article. Review.

6

HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin.

Chopra VS, Metzler M, Rasper DM, Engqvist-Goldstein AE, Singaraja R, Gan L, Fichter KM, McCutcheon K, Drubin D, Nicholson DW, Hayden MR. Chopra VS, et al. Mamm Genome. 2000 Nov;11(11):1006-15. doi: 10.1007/s003350010195. Mamm Genome. 2000. PMID: 11063258

7

Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo.

Leavitt BR, Guttman JA, Hodgson JG, Kimel GH, Singaraja R, Vogl AW, Hayden MR. Leavitt BR, et al. Am J Hum Genet. 2001 Feb;68(2):313-24. doi: 10.1086/318207. Epub 2000 Dec 20. Am J Hum Genet. 2001. PMID: 11133364 Free PMC article.

8

Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1.

Singaraja RR, Bocher V, James ER, Clee SM, Zhang LH, Leavitt BR, Tan B, Brooks-Wilson A, Kwok A, Bissada N, Yang YZ, Liu G, Tafuri SR, Fievet C, Wellington CL, Staels B, Hayden MR. Singaraja RR, et al. J Biol Chem. 2001 Sep 7;276(36):33969-79. doi: 10.1074/jbc.M102503200. Epub 2001 Jun 21. J Biol Chem. 2001. PMID: 11423537 Free article.

9

ABCA1 mRNA and protein distribution patterns predict multiple different roles and levels of regulation.

Wellington CL, Walker EK, Suarez A, Kwok A, Bissada N, Singaraja R, Yang YZ, Zhang LH, James E, Wilson JE, Francone O, McManus BM, Hayden MR. Wellington CL, et al. Lab Invest. 2002 Mar;82(3):273-83. doi: 10.1038/labinvest.3780421. Lab Invest. 2002. PMID: 11896206 Free article.

10

ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

Zwarts KY, Clee SM, Zwinderman AH, Engert JC, Singaraja R, Loubser O, James E, Roomp K, Hudson TJ, Jukema JW, Kastelein JJ, Hayden MR. Zwarts KY, et al. Clin Genet. 2002 Feb;61(2):115-25. doi: 10.1034/j.1399-0004.2002.610206.x. Clin Genet. 2002. PMID: 11940086

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