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Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice.
Chevre R, Trigueros-Motos L, Castaño D, Chua T, Corlianò M, Patankar JV, Sng L, Sim L, Juin TL, Carissimo G, Ng LFP, Yi CNJ, Eliathamby CC, Groen AK, Hayden MR, Singaraja RR. Chevre R, et al. Among authors: patankar jv. FASEB J. 2018 Jul;32(7):3792-3802. doi: 10.1096/fj.201701084RR. Epub 2018 Feb 26. FASEB J. 2018. PMID: 29481310
Loss of Cyp8b1 improves glucose homeostasis by increasing GLP-1.
Kaur A, Patankar JV, de Haan W, Ruddle P, Wijesekara N, Groen AK, Verchere CB, Singaraja RR, Hayden MR. Kaur A, et al. Among authors: patankar jv. Diabetes. 2015 Apr;64(4):1168-79. doi: 10.2337/db14-0716. Epub 2014 Oct 22. Diabetes. 2015. PMID: 25338812
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4.
Out C, Patankar JV, Doktorova M, Boesjes M, Bos T, de Boer S, Havinga R, Wolters H, Boverhof R, van Dijk TH, Smoczek A, Bleich A, Sachdev V, Kratky D, Kuipers F, Verkade HJ, Groen AK. Out C, et al. Among authors: patankar jv. J Hepatol. 2015 Sep;63(3):697-704. doi: 10.1016/j.jhep.2015.04.030. Epub 2015 May 27. J Hepatol. 2015. PMID: 26022694 Free PMC article.
Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Sachdev V, Leopold C, Bauer R, Patankar JV, Iqbal J, Obrowsky S, Boverhof R, Doktorova M, Scheicher B, Goeritzer M, Kolb D, Turnbull AV, Zimmer A, Hoefler G, Hussain MM, Groen AK, Kratky D. Sachdev V, et al. Among authors: patankar jv. Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1132-1141. doi: 10.1016/j.bbalip.2016.06.014. Epub 2016 Jun 23. Biochim Biophys Acta. 2016. PMID: 27344248 Free PMC article.
Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D. Radović B, et al. Among authors: patankar jv. Diabetologia. 2016 Aug;59(8):1743-52. doi: 10.1007/s00125-016-3968-6. Epub 2016 May 6. Diabetologia. 2016. PMID: 27153842 Free PMC article.
44 results