Tien J - Search Results

1

The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel.

Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan LY. Peters CJ, et al. Among authors: tien j. Neuron. 2018 Mar 7;97(5):1063-1077.e4. doi: 10.1016/j.neuron.2018.01.048. Epub 2018 Feb 22. Neuron. 2018. PMID: 29478917 Free PMC article.

2

Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC).

Tien J, Lee HY, Minor DL Jr, Jan YN, Jan LY. Tien J, et al. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6352-7. doi: 10.1073/pnas.1303672110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23576756 Free PMC article.

3

A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.

Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. Tien J, et al. Elife. 2014 Jun 30;3:e02772. doi: 10.7554/eLife.02772. Elife. 2014. PMID: 24980701 Free PMC article.

4

Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels.

Peters CJ, Yu H, Tien J, Jan YN, Li M, Jan LY. Peters CJ, et al. Among authors: tien j. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3547-52. doi: 10.1073/pnas.1502291112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733897 Free PMC article.

5

Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning.

Zhang Y, Zhang Z, Xiao S, Tien J, Le S, Le T, Jan LY, Yang H. Zhang Y, et al. Among authors: tien j. Neuron. 2017 Aug 30;95(5):1103-1111.e4. doi: 10.1016/j.neuron.2017.08.010. Neuron. 2017. PMID: 28858616 Free PMC article.

6

Cryo-EM structures of the TMEM16A calcium-activated chloride channel.

Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL Jr, Cheng Y, Jan LY. Dang S, et al. Among authors: tien j. Nature. 2017 Dec 21;552(7685):426-429. doi: 10.1038/nature25024. Epub 2017 Dec 13. Nature. 2017. PMID: 29236684 Free PMC article.

7

TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation.

Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan YN, Jan LY. Yang H, et al. Among authors: tien j. Cell. 2012 Sep 28;151(1):111-22. doi: 10.1016/j.cell.2012.07.036. Cell. 2012. PMID: 23021219 Free PMC article.

8

TMEM16C is involved in thermoregulation and protects rodent pups from febrile seizures.

Wang TA, Chen C, Huang F, Feng S, Tien J, Braz JM, Basbaum AI, Jan YN, Jan LY. Wang TA, et al. Among authors: tien j. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2023342118. doi: 10.1073/pnas.2023342118. Proc Natl Acad Sci U S A. 2021. PMID: 33972431 Free PMC article.

9

Long-range chromosomal engineering is more efficient in vitro than in vivo.

Olson LE, Tien J, South S, Reeves RH. Olson LE, et al. Among authors: tien j. Transgenic Res. 2005 Jun;14(3):325-32. doi: 10.1007/s11248-005-0389-6. Transgenic Res. 2005. PMID: 16145840

10

Corrigendum to "Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma" [Neoplasia, Volume 21, Issue 3 (2019) 322-330].

Choi JE, Verhaegen ME, Yazdani S, Malik R, Harms PW, Mangelberger D, Tien J, Cao X, Wang Y, Cieślik M, Gurkan J, Yazdani M, Jing X, Juckette K, Su F, Wang R, Zhou B, Apel IJ, Wang S, Dlugosz AA, Chinnaiyan AM. Choi JE, et al. Among authors: tien j. Neoplasia. 2024 May;51:100995. doi: 10.1016/j.neo.2024.100995. Epub 2024 Apr 4. Neoplasia. 2024. PMID: 38574506 Free PMC article. No abstract available.

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