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Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD.
Prokop JW, Yeo NC, Ottmann C, Chhetri SB, Florus KL, Ross EJ, Sosonkina N, Link BA, Freedman BI, Coppola CJ, McDermott-Roe C, Leysen S, Milroy LG, Meijer FA, Geurts AM, Rauscher FJ 3rd, Ramaker R, Flister MJ, Jacob HJ, Mendenhall EM, Lazar J. Prokop JW, et al. Among authors: ottmann c. J Am Soc Nephrol. 2018 May;29(5):1525-1535. doi: 10.1681/ASN.2017080856. Epub 2018 Feb 23. J Am Soc Nephrol. 2018. PMID: 29476007 Free PMC article.
Modulators of protein-protein interactions.
Milroy LG, Grossmann TN, Hennig S, Brunsveld L, Ottmann C. Milroy LG, et al. Among authors: ottmann c. Chem Rev. 2014 May 14;114(9):4695-748. doi: 10.1021/cr400698c. Epub 2014 Apr 15. Chem Rev. 2014. PMID: 24735440 Review. No abstract available.
A natural-product switch for a dynamic protein interface.
Scheepstra M, Nieto L, Hirsch AK, Fuchs S, Leysen S, Lam CV, in het Panhuis L, van Boeckel CA, Wienk H, Boelens R, Ottmann C, Milroy LG, Brunsveld L. Scheepstra M, et al. Among authors: ottmann c. Angew Chem Int Ed Engl. 2014 Jun 16;53(25):6443-8. doi: 10.1002/anie.201403773. Epub 2014 May 12. Angew Chem Int Ed Engl. 2014. PMID: 24821627
The renaissance of Ras.
Milroy LG, Ottmann C. Milroy LG, et al. Among authors: ottmann c. ACS Chem Biol. 2014 Nov 21;9(11):2447-58. doi: 10.1021/cb500555h. Epub 2014 Sep 23. ACS Chem Biol. 2014. PMID: 25148694 Review.
Stabilizer-Guided Inhibition of Protein-Protein Interactions.
Milroy LG, Bartel M, Henen MA, Leysen S, Adriaans JM, Brunsveld L, Landrieu I, Ottmann C. Milroy LG, et al. Among authors: ottmann c. Angew Chem Int Ed Engl. 2015 Dec 21;54(52):15720-4. doi: 10.1002/anie.201507976. Epub 2015 Nov 5. Angew Chem Int Ed Engl. 2015. PMID: 26537010
Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.
Stevers LM, Lam CV, Leysen SF, Meijer FA, van Scheppingen DS, de Vries RM, Carlile GW, Milroy LG, Thomas DY, Brunsveld L, Ottmann C. Stevers LM, et al. Among authors: ottmann c. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1152-61. doi: 10.1073/pnas.1516631113. Epub 2016 Feb 17. Proc Natl Acad Sci U S A. 2016. PMID: 26888287 Free PMC article.
Structural interface between LRRK2 and 14-3-3 protein.
Stevers LM, de Vries RM, Doveston RG, Milroy LG, Brunsveld L, Ottmann C. Stevers LM, et al. Among authors: ottmann c. Biochem J. 2017 Mar 23;474(7):1273-1287. doi: 10.1042/BCJ20161078. Biochem J. 2017. PMID: 28202711
172 results