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Cholesterol-enriched membrane microdomains are needed for insulin signaling and proliferation in hepatic cells.
Fonseca MC, França A, Florentino RM, Fonseca RC, Lima Filho ACM, Vidigal PTV, Oliveira AG, Dubuquoy L, Nathanson MH, Leite MF. Fonseca MC, et al. Among authors: vidigal ptv. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G80-G94. doi: 10.1152/ajpgi.00008.2018. Epub 2018 Feb 22. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29471671 Free PMC article.
Expression of the type 3 InsP3 receptor is a final common event in the development of hepatocellular carcinoma.
Guerra MT, Florentino RM, Franca A, Lima Filho AC, Dos Santos ML, Fonseca RC, Lemos FO, Fonseca MC, Kruglov E, Mennone A, Njei B, Gibson J, Guan F, Cheng YC, Ananthanarayanan M, Gu J, Jiang J, Zhao H, Lima CX, Vidigal PT, Oliveira AG, Nathanson MH, Leite MF. Guerra MT, et al. Gut. 2019 Sep;68(9):1676-1687. doi: 10.1136/gutjnl-2018-317811. Epub 2019 Jul 17. Gut. 2019. PMID: 31315892 Free PMC article.