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Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.
Volpi S, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Rodriguez LL, Aronson S, Cavallari LH, Denny JC, Dressler LG, Johnson JA, Klein TE, Leeder JS, Piquette-Miller M, Perera M, Rasmussen-Torvik LJ, Rehm HL, Ritchie MD, Skaar TC, Wagle N, Weinshilboum R, Weitzel KW, Wildin R, Wilson J, Manolio TA, Relling MV. Volpi S, et al. Among authors: skaar tc. Clin Pharmacol Ther. 2018 May;103(5):778-786. doi: 10.1002/cpt.1048. Epub 2018 Mar 30. Clin Pharmacol Ther. 2018. PMID: 29460415 Free PMC article. Review.
The pharmacogenetics research network: from SNP discovery to clinical drug response.
Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.
Clinically available pharmacogenomics tests.
Flockhart DA, Skaar T, Berlin DS, Klein TE, Nguyen AT. Flockhart DA, et al. Clin Pharmacol Ther. 2009 Jul;86(1):109-13. doi: 10.1038/clpt.2009.39. Epub 2009 Apr 15. Clin Pharmacol Ther. 2009. PMID: 19369936 Free PMC article. Review.
Antiestrogen pathway (aromatase inhibitor).
Desta Z, Nguyen A, Flockhart D, Skaar T, Fletcher R, Weinshilboum R, Berlin DS, Klein TE, Altman RB. Desta Z, et al. Pharmacogenet Genomics. 2009 Jul;19(7):554-5. doi: 10.1097/FPC.0b013e32832e0ec1. Pharmacogenet Genomics. 2009. PMID: 19512956 Free PMC article. No abstract available.
The emerging role of electronic medical records in pharmacogenomics.
Wilke RA, Xu H, Denny JC, Roden DM, Krauss RM, McCarty CA, Davis RL, Skaar T, Lamba J, Savova G. Wilke RA, et al. Clin Pharmacol Ther. 2011 Mar;89(3):379-86. doi: 10.1038/clpt.2010.260. Epub 2011 Jan 19. Clin Pharmacol Ther. 2011. PMID: 21248726 Free PMC article. Review.
Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age.
Desta Z, Kreutz Y, Nguyen AT, Li L, Skaar T, Kamdem LK, Henry NL, Hayes DF, Storniolo AM, Stearns V, Hoffmann E, Tyndale RF, Flockhart DA. Desta Z, et al. Clin Pharmacol Ther. 2011 Nov;90(5):693-700. doi: 10.1038/clpt.2011.174. Epub 2011 Oct 5. Clin Pharmacol Ther. 2011. PMID: 21975350 Free PMC article. Clinical Trial.
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype.
Crews KR, Gaedigk A, Dunnenberger HM, Klein TE, Shen DD, Callaghan JT, Kharasch ED, Skaar TC; Clinical Pharmacogenetics Implementation Consortium. Crews KR, et al. Among authors: skaar tc. Clin Pharmacol Ther. 2012 Feb;91(2):321-6. doi: 10.1038/clpt.2011.287. Epub 2011 Dec 28. Clin Pharmacol Ther. 2012. PMID: 22205192 Free PMC article.
Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants.
Hicks JK, Swen JJ, Thorn CF, Sangkuhl K, Kharasch ED, Ellingrod VL, Skaar TC, Müller DJ, Gaedigk A, Stingl JC; Clinical Pharmacogenetics Implementation Consortium. Hicks JK, et al. Among authors: skaar tc. Clin Pharmacol Ther. 2013 May;93(5):402-8. doi: 10.1038/clpt.2013.2. Epub 2013 Jan 16. Clin Pharmacol Ther. 2013. PMID: 23486447 Free PMC article. Review.
Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 update.
Crews KR, Gaedigk A, Dunnenberger HM, Leeder JS, Klein TE, Caudle KE, Haidar CE, Shen DD, Callaghan JT, Sadhasivam S, Prows CA, Kharasch ED, Skaar TC; Clinical Pharmacogenetics Implementation Consortium. Crews KR, et al. Among authors: skaar tc. Clin Pharmacol Ther. 2014 Apr;95(4):376-82. doi: 10.1038/clpt.2013.254. Epub 2014 Jan 23. Clin Pharmacol Ther. 2014. PMID: 24458010 Free PMC article. Review.
207 results