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A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.
Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL. Zhang X, et al. Among authors: boudreau rl. J Clin Invest. 2018 Mar 1;128(3):1154-1163. doi: 10.1172/JCI95710. Epub 2018 Feb 19. J Clin Invest. 2018. PMID: 29457789 Free PMC article.
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart.
Rasmussen TP, Wu Y, Joiner ML, Koval OM, Wilson NR, Luczak ED, Wang Q, Chen B, Gao Z, Zhu Z, Wagner BA, Soto J, McCormick ML, Kutschke W, Weiss RM, Yu L, Boudreau RL, Abel ED, Zhan F, Spitz DR, Buettner GR, Song LS, Zingman LV, Anderson ME. Rasmussen TP, et al. Among authors: boudreau rl. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9129-34. doi: 10.1073/pnas.1504705112. Epub 2015 Jul 7. Proc Natl Acad Sci U S A. 2015. PMID: 26153425 Free PMC article.
Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.
Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Vikram A, et al. Among authors: boudreau rl. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191886 Free PMC article.
Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models.
Wang Y, Chen B, Huang CK, Guo A, Wu J, Zhang X, Chen R, Chen C, Kutschke W, Weiss RM, Boudreau RL, Margulies KB, Hong J, Song LS. Wang Y, et al. Among authors: boudreau rl. JACC Basic Transl Sci. 2018 Aug 28;3(4):503-517. doi: 10.1016/j.jacbts.2018.05.004. eCollection 2018 Aug. JACC Basic Transl Sci. 2018. PMID: 30175274 Free PMC article.
Modulation of the cardiac sodium channel NaV1.5 peak and late currents by NAD+ precursors.
Matasic DS, Yoon JY, McLendon JM, Mehdi H, Schmidt MS, Greiner AM, Quinones P, Morgan GM, Boudreau RL, Irani K, Brenner C, London B. Matasic DS, et al. Among authors: boudreau rl. J Mol Cell Cardiol. 2020 Apr;141:70-81. doi: 10.1016/j.yjmcc.2020.01.013. Epub 2020 Mar 21. J Mol Cell Cardiol. 2020. PMID: 32209328 Free PMC article.
48 results