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Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin.
Sundberg M, Tochitsky I, Buchholz DE, Winden K, Kujala V, Kapur K, Cataltepe D, Turner D, Han MJ, Woolf CJ, Hatten ME, Sahin M. Sundberg M, et al. Among authors: woolf cj. Mol Psychiatry. 2018 Nov;23(11):2167-2183. doi: 10.1038/s41380-018-0018-4. Epub 2018 Feb 15. Mol Psychiatry. 2018. PMID: 29449635 Free PMC article.
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ. Wainger BJ, et al. Among authors: woolf cj. Nat Neurosci. 2015 Jan;18(1):17-24. doi: 10.1038/nn.3886. Epub 2014 Nov 24. Nat Neurosci. 2015. PMID: 25420066 Free PMC article.
Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS.
Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett LB, Singh B, Lee S, Crisman T, Gao F, Li S, Kapur K, Geschwind DH, Kosik KS, Coppola G, He Z, Carmichael ST, Benowitz LI, Costigan M, Woolf CJ. Omura T, et al. Among authors: woolf cj. Neuron. 2015 Jun 3;86(5):1215-27. doi: 10.1016/j.neuron.2015.05.005. Epub 2015 May 21. Neuron. 2015. PMID: 26004914 Free PMC article.
Diltiazem Promotes Regenerative Axon Growth.
Huebner EA, Budel S, Jiang Z, Omura T, Ho TS, Barrett L, Merkel JS, Pereira LM, Andrews NA, Wang X, Singh B, Kapur K, Costigan M, Strittmatter SM, Woolf CJ. Huebner EA, et al. Among authors: woolf cj. Mol Neurobiol. 2019 Jun;56(6):3948-3957. doi: 10.1007/s12035-018-1349-5. Epub 2018 Sep 19. Mol Neurobiol. 2019. PMID: 30232777 Free PMC article.
Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker.
Tochitsky I, Jo S, Andrews N, Kotoda M, Doyle B, Shim J, Talbot S, Roberson D, Lee J, Haste L, Jordan SM, Levy BD, Bean BP, Woolf CJ. Tochitsky I, et al. Among authors: woolf cj. Br J Pharmacol. 2021 Oct;178(19):3905-3923. doi: 10.1111/bph.15531. Epub 2021 Jun 21. Br J Pharmacol. 2021. PMID: 33988876 Free PMC article.
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons.
Cheng YC, Snavely A, Barrett LB, Zhang X, Herman C, Frost DJ, Riva P, Tochitsky I, Kawaguchi R, Singh B, Ivanis J, Huebner EA, Arvanites A, Oza V, Davidow L, Maeda R, Sakuma M, Grantham A, Wang Q, Chang AN, Pfaff K, Costigan M, Coppola G, Rubin LL, Schwer B, Alt FW, Woolf CJ. Cheng YC, et al. Among authors: woolf cj. Cell Rep. 2021 Sep 7;36(10):109666. doi: 10.1016/j.celrep.2021.109666. Cell Rep. 2021. PMID: 34496254 Free PMC article.
446 results