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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration.
Muehlan C, Boehler M, Brooks S, Zuiker R, van Gerven J, Dingemanse J. Muehlan C, et al. J Psychopharmacol. 2020 Mar;34(3):326-335. doi: 10.1177/0269881119882854. Epub 2019 Oct 23. J Psychopharmacol. 2020. PMID: 31642731 Clinical Trial.
Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects.
Berger B, Brooks S, Zuiker R, Richard M, Muehlan C, Dingemanse J. Berger B, et al. Among authors: muehlan c. CNS Drugs. 2020 Dec;34(12):1253-1266. doi: 10.1007/s40263-020-00768-8. Epub 2020 Nov 18. CNS Drugs. 2020. PMID: 33205362 Clinical Trial.
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