Croft M - Search Results

1

Accelerated Development of the Dual Orexin Receptor Antagonist ACT-541468: Integration of a Microtracer in a First-in-Human Study.

Muehlan C, Heuberger J, Juif PE, Croft M, van Gerven J, Dingemanse J. Muehlan C, et al. Among authors: croft m. Clin Pharmacol Ther. 2018 Nov;104(5):1022-1029. doi: 10.1002/cpt.1046. Epub 2018 Mar 10. Clin Pharmacol Ther. 2018. PMID: 29446069 Clinical Trial.

2

Metabolism of the Dual Orexin Receptor Antagonist ACT-541468, Based on Microtracer/ Accelerator Mass Spectrometry.

Muehlan C, Fischer H, Zimmer D, Aissaoui H, Grimont J, Boss C, Croft M, van Gerven J, Krähenbühl S, Dingemanse J. Muehlan C, et al. Among authors: croft m. Curr Drug Metab. 2019;20(4):254-265. doi: 10.2174/1389200220666190206141814. Curr Drug Metab. 2019. PMID: 30727881 Clinical Trial.

3

Pharmacokinetics and metabolism of [¹⁴C]-tozadenant (SYN-115), a novel A2a receptor antagonist ligand, in healthy volunteers.

Mancel V, Mathy FX, Boulanger P, English S, Croft M, Kenney C, Knott T, Stockis A, Bani M. Mancel V, et al. Among authors: croft m. Xenobiotica. 2017 Aug;47(8):705-718. doi: 10.1080/00498254.2016.1221164. Epub 2016 Sep 2. Xenobiotica. 2017. PMID: 27489076 Clinical Trial.

4

Absolute Bioavailability, Mass Balance, and Metabolic Profiling Assessment of [¹⁴ C]-Belumosudil in Healthy Men: A Phase 1, Open-Label, 2-Part Study.

Schueller O, Skucas E, Regev G, Shaw I, Singh N, Sanghvi M, Croft M, Lohmer L, Alabanza A, Patel J. Schueller O, et al. Among authors: croft m. Clin Pharmacol Drug Dev. 2022 Jul;11(7):786-794. doi: 10.1002/cpdd.1085. Epub 2022 Mar 1. Clin Pharmacol Drug Dev. 2022. PMID: 35231159 Clinical Trial.

5

Disposition and Mass Balance of Etrasimod in Healthy Subjects and In Vitro Determination of the Enzymes Responsible for Its Oxidative Metabolism.

Lee CA, Oh DA, Tang Y, Yi P, Bashir M, English S, Croft M, Blackburn A, Bloom S, Gilder K, Grundy JS. Lee CA, et al. Among authors: croft m. Clin Pharmacol Drug Dev. 2023 Jun;12(6):553-571. doi: 10.1002/cpdd.1255. Epub 2023 May 3. Clin Pharmacol Drug Dev. 2023. PMID: 37132407

6

Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry.

Lee JJ, Seraj J, Yoshida K, Mizuguchi H, Strychor S, Fiejdasz J, Faulkner T, Parise RA, Fawcett P, Pollice L, Mason S, Hague J, Croft M, Nugteren J, Tedder C, Sun W, Chu E, Beumer JH. Lee JJ, et al. Among authors: croft m. Cancer Chemother Pharmacol. 2016 Mar;77(3):515-26. doi: 10.1007/s00280-016-2965-2. Epub 2016 Jan 19. Cancer Chemother Pharmacol. 2016. PMID: 26787503 Free PMC article. Clinical Trial.

7

Pharmacokinetics, absorption, and excretion of radiolabeled revexepride: a Phase I clinical trial using a microtracer and accelerator mass spectrometry-based approach.

Flach S, Croft M, Ding J, Budhram R, Pankratz T, Pennick M, Scarfe G, Troy S, Getsy J. Flach S, et al. Among authors: croft m. Drug Des Devel Ther. 2016 Sep 27;10:3125-3132. doi: 10.2147/DDDT.S107843. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 27729771 Free PMC article. Clinical Trial.

8

Predicting drug candidate victims of drug-drug interactions, using microdosing.

Croft M, Keely B, Morris I, Tann L, Lappin G. Croft M, et al. Clin Pharmacokinet. 2012 Apr 1;51(4):237-46. doi: 10.2165/11597070-000000000-00000. Clin Pharmacokinet. 2012. PMID: 22335429

9

Sex as a risk factor regarding presbyopia in the rhesus monkey.

Croft MA, Mcdonald JP, Kiland J, Mattison JA, Roth GS, Ingram D, Kaufman PL. Croft MA, et al. PLoS One. 2024 Apr 18;19(4):e0300476. doi: 10.1371/journal.pone.0300476. eCollection 2024. PLoS One. 2024. PMID: 38635668 Free PMC article.

10

LIGHT signaling through LTβR and HVEM in keratinocytes promotes psoriasis and atopic dermatitis-like skin inflammation.

Gupta RK, Figueroa DS, Fung K, Miki H, Miller J, Ay F, Croft M. Gupta RK, et al. Among authors: croft m. J Autoimmun. 2024 Apr;144:103177. doi: 10.1016/j.jaut.2024.103177. Epub 2024 Feb 17. J Autoimmun. 2024. PMID: 38368767

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