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Tomatidine and analog FC04-100 possess bactericidal activities against Listeria, Bacillus and Staphylococcus spp.
BMC Pharmacol Toxicol. 2018 Feb 13;19(1):7. doi: 10.1186/s40360-018-0197-2.
BMC Pharmacol Toxicol. 2018.
PMID: 29439722
Free PMC article.
Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C.
Lamontagne Boulet M, Isabelle C, Guay I, Brouillette E, Langlois JP, Jacques PÉ, Rodrigue S, Brzezinski R, Beauregard PB, Bouarab K, Boyapelly K, Boudreault PL, Marsault É, Malouin F.
Lamontagne Boulet M, et al. Among authors: guay i.
Antimicrob Agents Chemother. 2018 May 25;62(6):e02197-17. doi: 10.1128/AAC.02197-17. Print 2018 Jun.
Antimicrob Agents Chemother. 2018.
PMID: 29610201
Free PMC article.
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Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression.
Mitchell G, Lafrance M, Boulanger S, Séguin DL, Guay I, Gattuso M, Marsault E, Bouarab K, Malouin F.
Mitchell G, et al. Among authors: guay i.
J Antimicrob Chemother. 2012 Mar;67(3):559-68. doi: 10.1093/jac/dkr510. Epub 2011 Nov 30.
J Antimicrob Chemother. 2012.
PMID: 22129590
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Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus.
Chagnon F, Guay I, Bonin MA, Mitchell G, Bouarab K, Malouin F, Marsault É.
Chagnon F, et al. Among authors: guay i.
Eur J Med Chem. 2014 Jun 10;80:605-20. doi: 10.1016/j.ejmech.2013.11.019.
Eur J Med Chem. 2014.
PMID: 24877760
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Bactericidal Activity of the Bacterial ATP Synthase Inhibitor Tomatidine and the Combination of Tomatidine and Aminoglycoside Against Persistent and Virulent Forms of Staphylococcus aureus.
Langlois JP, Millette G, Guay I, Dubé-Duquette A, Chamberland S, Jacques PÉ, Rodrigue S, Bouarab K, Marsault É, Malouin F.
Langlois JP, et al. Among authors: guay i.
Front Microbiol. 2020 May 5;11:805. doi: 10.3389/fmicb.2020.00805. eCollection 2020.
Front Microbiol. 2020.
PMID: 32431678
Free PMC article.
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Modification of genetic regulation of a heterologous chitosanase gene in Streptomyces lividans TK24 leads to chitosanase production in the absence of chitosan.
Dubeau MP, Guay I, Brzezinski R.
Dubeau MP, et al. Among authors: guay i.
Microb Cell Fact. 2011 Feb 10;10:7. doi: 10.1186/1475-2859-10-7.
Microb Cell Fact. 2011.
PMID: 21310076
Free PMC article.
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Effect of Polymer Viscosity and Polymerization Kinetics on the Electrical Response of Carbon Nanotube Yarn/Vinyl Ester Monofilament Composites.
Rodríguez-Uicab O, Guay I, Abot JL, Avilés F.
Rodríguez-Uicab O, et al. Among authors: guay i.
Polymers (Basel). 2021 Mar 4;13(5):783. doi: 10.3390/polym13050783.
Polymers (Basel). 2021.
PMID: 33806431
Free PMC article.
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