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A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A. Casini A, et al. Among authors: lorenzin f. Nat Biotechnol. 2018 Mar;36(3):265-271. doi: 10.1038/nbt.4066. Epub 2018 Jan 29. Nat Biotechnol. 2018. PMID: 29431739 Free PMC article.
ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation.
Lorenzoni M, De Felice D, Beccaceci G, Di Donato G, Foletto V, Genovesi S, Bertossi A, Cambuli F, Lorenzin F, Savino A, Avalle L, Cimadamore A, Montironi R, Weber V, Carbone FG, Barbareschi M, Demichelis F, Romanel A, Poli V, Del Sal G, Julio MK, Gaspari M, Alaimo A, Lunardi A. Lorenzoni M, et al. Among authors: lorenzin f. Cancer Lett. 2022 May 28;534:215612. doi: 10.1016/j.canlet.2022.215612. Epub 2022 Mar 5. Cancer Lett. 2022. PMID: 35259458 Free PMC article.
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.
Walz S, Lorenzin F, Morton J, Wiese KE, von Eyss B, Herold S, Rycak L, Dumay-Odelot H, Karim S, Bartkuhn M, Roels F, Wüstefeld T, Fischer M, Teichmann M, Zender L, Wei CL, Sansom O, Wolf E, Eilers M. Walz S, et al. Among authors: lorenzin f. Nature. 2014 Jul 24;511(7510):483-7. doi: 10.1038/nature13473. Epub 2014 Jul 9. Nature. 2014. PMID: 25043018 Free PMC article.
15 results