Matsukawa J - Search Results

1

Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis.

Amano Y, Tsuchiya S, Imai M, Tohyama K, Matsukawa J, Isono O, Yasuno H, Enya K, Koumura E, Nagabukuro H. Amano Y, et al. Among authors: matsukawa j. Biochem Biophys Res Commun. 2018 Feb 26;497(1):207-213. doi: 10.1016/j.bbrc.2018.02.055. Epub 2018 Feb 9. Biochem Biophys Res Commun. 2018. PMID: 29428719

2

Exploration of pyrrole derivatives to find an effective potassium-competitive acid blocker with moderately long-lasting suppression of gastric acid secretion.

Nishida H, Fujimori I, Arikawa Y, Hirase K, Ono K, Nakai K, Inatomi N, Hori Y, Matsukawa J, Fujioka Y, Imanishi A, Fukui H, Itoh F. Nishida H, et al. Among authors: matsukawa j. Bioorg Med Chem. 2017 Jul 1;25(13):3447-3460. doi: 10.1016/j.bmc.2017.04.034. Epub 2017 Apr 27. Bioorg Med Chem. 2017. PMID: 28483454

3

A comparative study on the modes of action of TAK-438, a novel potassium-competitive acid blocker, and lansoprazole in primary cultured rabbit gastric glands.

Matsukawa J, Hori Y, Nishida H, Kajino M, Inatomi N. Matsukawa J, et al. Biochem Pharmacol. 2011 May 1;81(9):1145-51. doi: 10.1016/j.bcp.2011.02.009. Epub 2011 Mar 1. Biochem Pharmacol. 2011. PMID: 21371447

4

Daikenchuto (TU-100) Suppresses Tumor Development in the Azoxymethane and APC^min/+ Mouse Models of Experimental Colon Cancer.

Hasebe T, Matsukawa J, Ringus D, Miyoshi J, Hart J, Kaneko A, Yamamoto M, Kono T, Fujiya M, Kohgo Y, Wang CZ, Yuan CS, Bissonnette M, Musch MW, Chang EB. Hasebe T, et al. Among authors: matsukawa j. Phytother Res. 2017 Jan;31(1):90-99. doi: 10.1002/ptr.5735. Epub 2016 Oct 12. Phytother Res. 2017. PMID: 27730672 Free PMC article.

5

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.

Nishida H, Arikawa Y, Hirase K, Imaeda T, Inatomi N, Hori Y, Matsukawa J, Fujioka Y, Hamada T, Iida M, Nishitani M, Imanishi A, Fukui H, Itoh F, Kajino M. Nishida H, et al. Among authors: matsukawa j. Bioorg Med Chem. 2017 Jul 1;25(13):3298-3314. doi: 10.1016/j.bmc.2017.04.014. Epub 2017 Apr 13. Bioorg Med Chem. 2017. PMID: 28442261

6

[Pharmacological characteristics and clinical efficacies of a novel potassium-competitive acid blocker, vonoprazan fumarate].

Matsukawa J, Inatomi N, Nishida H, Tsukimi Y. Matsukawa J, et al. Nihon Yakurigaku Zasshi. 2018;152(3):104-110. doi: 10.1254/fpj.152.104. Nihon Yakurigaku Zasshi. 2018. PMID: 30185727 Japanese.

7

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockers.

Imaeda T, Ono K, Nakai K, Hori Y, Matsukawa J, Takagi T, Fujioka Y, Tarui N, Kondo M, Imanishi A, Inatomi N, Kajino M, Itoh F, Nishida H. Imaeda T, et al. Among authors: matsukawa j. Bioorg Med Chem. 2017 Jul 15;25(14):3719-3735. doi: 10.1016/j.bmc.2017.05.012. Epub 2017 May 6. Bioorg Med Chem. 2017. PMID: 28522264

8

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438), a novel and potent potassium-competitive acid blocker for the treatment of acid-related diseases.

Hori Y, Imanishi A, Matsukawa J, Tsukimi Y, Nishida H, Arikawa Y, Hirase K, Kajino M, Inatomi N. Hori Y, et al. Among authors: matsukawa j. J Pharmacol Exp Ther. 2010 Oct;335(1):231-8. doi: 10.1124/jpet.110.170274. Epub 2010 Jul 12. J Pharmacol Exp Ther. 2010. PMID: 20624992

9

A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals.

Hori Y, Matsukawa J, Takeuchi T, Nishida H, Kajino M, Inatomi N. Hori Y, et al. Among authors: matsukawa j. J Pharmacol Exp Ther. 2011 Jun;337(3):797-804. doi: 10.1124/jpet.111.179556. Epub 2011 Mar 16. J Pharmacol Exp Ther. 2011. PMID: 21411494

10

Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).

Arikawa Y, Nishida H, Kurasawa O, Hasuoka A, Hirase K, Inatomi N, Hori Y, Matsukawa J, Imanishi A, Kondo M, Tarui N, Hamada T, Takagi T, Takeuchi T, Kajino M. Arikawa Y, et al. Among authors: matsukawa j. J Med Chem. 2012 May 10;55(9):4446-56. doi: 10.1021/jm300318t. Epub 2012 Apr 30. J Med Chem. 2012. PMID: 22512618

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